Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress. - Wikidata - awgldk - TriplyDB

Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress.

Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress.

http://www.wikidata.org/entity/Q36995409

about

High-dose irradiation induces cell cycle arrest, apoptosis, and developmental defects during Drosophila oogenesis Endoreplication: polyploidy with purpose Endoreplication Endoreplication and polyploidy: insights into development and disease Canonical and atypical E2Fs regulate the mammalian endocycle Phylogeny and function of the invertebrate p53 superfamily RBX1 (RING box protein 1) E3 ubiquitin ligase is required for genomic integrity by modulating DNA replication licensing proteins Drug-induced cell cycle modulation leading to cell-cycle arrest, nuclear mis-segregation, or endoreplication.Transient endoreplication down-regulates the kinesin-14 HSET and contributes to genomic instability.Cracking open cell death in the Drosophila ovary.Cytoplasmic localization of p21 protects trophoblast giant cells from DNA damage induced apoptosis.One-hit wonders of genomic instability.Low levels of p53 protein and chromatin silencing of p53 target genes repress apoptosis in Drosophila endocycling cells.Cell type-dependent requirement for PIP box-regulated Cdt1 destruction during S phase.Genome-wide expression analysis identifies a modulator of ionizing radiation-induced p53-independent apoptosis in Drosophila melanogaster Incomplete replication generates somatic DNA alterations within Drosophila polytene salivary gland cells.Inducing extra copies of the Hsp70 gene in Drosophila melanogaster increases energetic demand.Aging and insulin signaling differentially control normal and tumorous germline stem cells.Checkpoint kinase 1 prevents cell cycle exit linked to terminal cell differentiation.Safeguarding genetic information in Drosophila.The expanding implications of polyploidy.Analysis of model replication origins in Drosophila reveals new aspects of the chromatin landscape and its relationship to origin activity and the prereplicative complex Radiosensitization of human pancreatic cancer cells by MLN4924, an investigational NEDD8-activating enzyme inhibitor.Regulation of DNA replication during development.Distinct activities of the anaphase-promoting complex/cyclosome (APC/C) in mouse embryonic cells.Understanding replication fork progression, stability, and chromosome fragility by exploiting the Suppressor of Underreplication protein."The Octet": Eight Protein Kinases that Control Mammalian DNA Replication.Expression of an S phase-stabilized version of the CDK inhibitor Dacapo can alter endoreplication.The function of Drosophila p53 isoforms in apoptosis.Fundamental differences in endoreplication in mammals and Drosophila revealed by analysis of endocycling and endomitotic cells Making big cells: one size does not fit all.Different cell cycle modifications repress apoptosis at different steps independent of developmental signaling in Drosophila.The development of a monoclonal antibody recognizing the Drosophila melanogaster phosphorylated histone H2A variant (γ-H2AV).Methylation of histone H4 lysine 20 by PR-Set7 ensures the integrity of late replicating sequence domains in Drosophila Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy.Genome Duplication: The Heartbeat of Developing Organisms.Developmentally programmed endoreduplication in animals.Induction of endocycles represses apoptosis independently of differentiation and predisposes cells to genome instability.Somatic polyploidy promotes cell function under stress and energy depletion: evidence from tissue-specific mammal transcriptome.When bigger is better: the role of polyploidy in organogenesis.

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P2860

Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress.

http://www.wikidata.org/entity/Q36995409

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress.

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type

label

Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress.

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prefLabel

Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress.

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Genes & Development

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Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress.

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P2093

Alexis Kolpakas

http://www.w3.org/2001/XMLSchema#string

Brian R Calvi

http://www.w3.org/2001/XMLSchema#string

Katherine Murnen

http://www.w3.org/2001/XMLSchema#string

Shahina B Maqbool

http://www.w3.org/2001/XMLSchema#string

Sonam Mehrotra

http://www.w3.org/2001/XMLSchema#string

P2860

Temporal analysis of meiotic DNA double-strand break formation and repair in Drosophila females

New insights into cell cycle control from the Drosophila endocycle

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

Geminin, an inhibitor of DNA replication, is degraded during mitosis

Disruption of mechanisms that prevent rereplication triggers a DNA damage response

Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage

Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint

Drosophila double parked: a conserved, essential replication protein that colocalizes with the origin recognition complex and links DNA replication with mitosis and the down-regulation of S phase transcripts

The anaphase-promoting complex/cyclosome (APC/C) is required for rereplication control in endoreplication cycles

Mechanisms to control rereplication and implications for cancer.

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3158-3171

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scholarly article

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10.1101/GAD.1710208

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22

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22

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2008-11-01T00:00:00Z

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19056894

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2593612

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