Disruption of mechanisms that prevent rereplication triggers a DNA damage response - Wikidata - awgldk - TriplyDB

Disruption of mechanisms that prevent rereplication triggers a DNA damage response

Disruption of mechanisms that prevent rereplication triggers a DNA damage response

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An overview of Cdk1-controlled targets and processes Genome-wide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant.Prevention of DNA re-replication in eukaryotic cells Re-replication of a centromere induces chromosomal instability and aneuploidy The Mck1 GSK-3 kinase inhibits the activity of Clb2-Cdk1 post-nuclear division Reverse genetic analysis of the yeast RSC chromatin remodeler reveals a role for RSC3 and SNF5 homolog 1 in ploidy maintenance A yeast GSK-3 kinase Mck1 promotes Cdc6 degradation to inhibit DNA re-replication.Replication fork instability and the consequences of fork collisions from rereplication Ubiquitylation, neddylation and the DNA damage response The Mre11/Rad50/Nbs1 complex plays an important role in the prevention of DNA rereplication in mammalian cells.Checkpoint effects and telomere amplification during DNA re-replication in fission yeast.CDK phosphorylation of a novel NLS-NES module distributed between two subunits of the Mcm2-7 complex prevents chromosomal rereplication Homologous recombination is a primary pathway to repair DNA double-strand breaks generated during DNA rereplication Single-stranded annealing induced by re-initiation of replication origins provides a novel and efficient mechanism for generating copy number expansion via non-allelic homologous recombination.Genome-wide analysis of re-replication reveals inhibitory controls that target multiple stages of replication initiation Roles of the CDK phosphorylation sites of yeast Cdc6 in chromatin binding and rereplication.Cyclin and cyclin-dependent kinase substrate requirements for preventing rereplication reveal the need for concomitant activation and inhibition.Cdc6 degradation requires phosphodegron created by GSK-3 and Cdk1 for SCFCdc4 recognition in Saccharomyces cerevisiae.Host factors that control long terminal repeat retrotransposons in Saccharomyces cerevisiae: implications for regulation of mammalian retroviruses Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damage The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted.DNA replication origin function is promoted by H3K4 di-methylation in Saccharomyces cerevisiae Cdt1 and Cdc6 are destabilized by rereplication-induced DNA damage.Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress.Plasma membrane/cell wall perturbation activates a novel cell cycle checkpoint during G1 in Saccharomyces cerevisiae.Analysis of re-replication from deregulated origin licensing by DNA fiber spreading Repression of nascent strand elongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts.Distinct activities of the related protein kinases Cdk1 and Ime2 Frequent occurrence of large duplications at reciprocal genomic rearrangement breakpoints in multiple myeloma and other tumors.Specific genetic interactions between spindle assembly checkpoint proteins and B-Type cyclins in Saccharomyces cerevisiae.Multiple mechanisms contribute to double-strand break repair at rereplication forks in Drosophila follicle cells.Prevention of DNA Rereplication Through a Meiotic Recombination Checkpoint Response.Large-scale heterochromatin remodeling linked to overreplication-associated DNA damage.Nucleosomes in the neighborhood: new roles for chromatin modifications in replication origin control.Non-Canonical Replication Initiation: You're Fired!Cullin-RING E3 Ubiquitin Ligases: Bridges to Destruction.CDC6 expression is regulated by lineage-specific transcription factor GATA1.Loss of DNA replication control is a potent inducer of gene amplification.Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision.CDK prevents Mcm2-7 helicase loading by inhibiting Cdt1 interaction with Orc6

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Disruption of mechanisms that prevent rereplication triggers a DNA damage response

http://www.wikidata.org/entity/Q24529993

description

2005 nî lūn-bûn

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2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

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2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Disruption of mechanisms that prevent rereplication triggers a DNA damage response

@ast

Disruption of mechanisms that prevent rereplication triggers a DNA damage response

@en

Disruption of mechanisms that prevent rereplication triggers a DNA damage response

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Disruption of mechanisms that prevent rereplication triggers a DNA damage response

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label

Disruption of mechanisms that prevent rereplication triggers a DNA damage response

@ast

Disruption of mechanisms that prevent rereplication triggers a DNA damage response

@en

Disruption of mechanisms that prevent rereplication triggers a DNA damage response

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Disruption of mechanisms that prevent rereplication triggers a DNA damage response

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prefLabel

Disruption of mechanisms that prevent rereplication triggers a DNA damage response

@ast

Disruption of mechanisms that prevent rereplication triggers a DNA damage response

@en

Disruption of mechanisms that prevent rereplication triggers a DNA damage response

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Disruption of mechanisms that prevent rereplication triggers a DNA damage response

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MCB.25.15.6707-6721.2005

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Molecular and Cellular Biology

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Disruption of mechanisms that prevent rereplication triggers a DNA damage response

@en

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Amy E Ikui

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Benjamin J Drapkin

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Frederick R Cross

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Vincent Archambault

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P2860

The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae

Loss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damage

Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint

Loss of Geminin induces rereplication in the presence of functional p53

Mre11 assembles linear DNA fragments into DNA damage signaling complexes

Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase

An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast.

Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair.

Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs.

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6707-21

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3320412

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10.1128/MCB.25.15.6707-6721.2005

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15

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