INK4a/ARF limits the expansion of cells suffering from replication stress - Wikidata - awgldk - TriplyDB

INK4a/ARF limits the expansion of cells suffering from replication stress

INK4a/ARF limits the expansion of cells suffering from replication stress

http://www.wikidata.org/entity/Q37017649

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Rapamycin induces pluripotent genes associated with avoidance of replicative senescence Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.Regulation and roles of Cdc7 kinase under replication stress.Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice.Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation.Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells.p19(Arf) is required for the cellular response to chronic DNA damage The Mre11 complex suppresses oncogene-driven breast tumorigenesis and metastasis.IGF-binding protein 2 is a candidate target of therapeutic potential in cancer.MKK7 and ARF: new players in the DNA damage response scenery.INK4a/ARF-dependent senescence upon persistent replication stress.The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liver

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INK4a/ARF limits the expansion of cells suffering from replication stress

http://www.wikidata.org/entity/Q37017649

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article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 15 May 2013

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vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

@cs

name

INK4a/ARF limits the expansion of cells suffering from replication stress

@en

INK4a/ARF limits the expansion of cells suffering from replication stress.

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type

label

INK4a/ARF limits the expansion of cells suffering from replication stress

@en

INK4a/ARF limits the expansion of cells suffering from replication stress.

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prefLabel

INK4a/ARF limits the expansion of cells suffering from replication stress

@en

INK4a/ARF limits the expansion of cells suffering from replication stress.

@nl

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INK4a/ARF limits the expansion of cells suffering from replication stress

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Angela Monasor

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Carolina Navas

http://www.w3.org/2001/XMLSchema#string

Gonzalo Gomez

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Matilde Murga

http://www.w3.org/2001/XMLSchema#string

P2860

A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

The DNA-damage response in human biology and disease

Targeting ATR and Chk1 kinases for cancer treatment: a new model for new (and old) drugs

The DNA Damage Response: Making It Safe to Play with Knives

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

A cell cycle regulator potentially involved in genesis of many tumor types

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

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1948-1954

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scholarly article

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10.4161/CC.25017

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12

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12

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David G. Pisano

Andrés J López-Contreras

Oscar Fernandez-Capetillo

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2013-05-15T00:00:00Z

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236910985

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23676215

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3712892

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