Mechanisms of disease: the PI3K-Akt-PTEN signaling node--an intercept point for the control of angiogenesis in brain tumors.
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Not so Fast: Co-Requirements for Sonic Hedgehog Induced Brain TumorigenesisS100B Protein Regulates Astrocyte Shape and Migration via Interaction with Src Kinase: IMPLICATIONS FOR ASTROCYTE DEVELOPMENT, ACTIVATION, AND TUMOR GROWTHTargeting the PI3K/mTOR axis, alone and in combination with autophagy blockade, for the treatment of malignant peripheral nerve sheath tumorsHeterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma.In vitro evaluation of pan-PI3-kinase inhibitor SF1126 in trastuzumab-sensitive and trastuzumab-resistant HER2-over-expressing breast cancer cells.Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression.Monitoring response to anti-angiogenic mTOR inhibitor therapy in vivo using 111In-bevacizumabBrain angiogenesis in developmental and pathological processes: mechanism and therapeutic intervention in brain tumors.Discovery of novel anticancer therapeutics targeting the PI3K/Akt/mTOR pathway.PI3K contributed to modulation of spinal nociceptive information related to ephrinBs/EphBsActivation of miR-21 by STAT3 induces proliferation and suppresses apoptosis in nasopharyngeal carcinoma by targeting PTEN geneA novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells.The PI-3 kinase-Akt-MDM2-survivin signaling axis in high-risk neuroblastoma: a target for PI-3 kinase inhibitor intervention.C-reactive protein inhibits survivin expression via Akt/mTOR pathway downregulation by PTEN expression in cardiac myocytes.Pathway profiling and rational trial design for studies in advanced stage cervical carcinoma: a review and a perspective.Chronic Dietary Administration of the Glycolytic Inhibitor 2-Deoxy-D-Glucose (2-DG) Inhibits the Growth of Implanted Ehrlich's Ascites Tumor in MiceRelevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cellsAntiangiogenic therapy for glioma.MicroRNA-20b (miR-20b) Promotes the Proliferation, Migration, Invasion, and Tumorigenicity in Esophageal Cancer Cells via the Regulation of Phosphatase and Tensin Homologue Expression.Multifaceted roles of PTEN and TSC orchestrate growth and differentiation of Drosophila blood progenitors.Dopamine D2 receptor-mediated Akt/PKB signalling: initiation by the D2S receptor and role in quinpirole-induced behavioural activation.Targeting annexin A2 reduces tumorigenesis and therapeutic resistance of nasopharyngeal carcinoma.Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β.Thematic review series: sphingolipids. Ganglioside GM3 suppresses the proangiogenic effects of vascular endothelial growth factor and ganglioside GD1a.MiR-214 regulate gastric cancer cell proliferation, migration and invasion by targeting PTEN.Different response of human glioma tumor-initiating cells to epidermal growth factor receptor kinase inhibitors.Combination therapy for malignant glioma based on PTEN status.Brain cancer stem cells display preferential sensitivity to Akt inhibition.Improving the prognosis for patients with glioblastoma: the rationale for targeting Src.Correlation of NEDD4-1 and PTEN expression with the invasive capacity of pituitary adenomas.Glioma stem cell signaling: therapeutic opportunities and challenges.Current and emerging molecular targets in glioma.The impact of tumor microenvironment on cancer treatment and its modulation by direct and indirect antivascular strategies.MicroRNA-196a overexpression promotes cell proliferation and inhibits cell apoptosis through PTEN/Akt/FOXO1 pathway.Down-regulation of PTEN expression modulated by dysregulated miR-21 contributes to the progression of esophageal cancer.Cannabinoids inhibit energetic metabolism and induce AMPK-dependent autophagy in pancreatic cancer cells.MicroRNA-32 (miR-32) regulates phosphatase and tensin homologue (PTEN) expression and promotes growth, migration, and invasion in colorectal carcinoma cells.Exploration of Involved Key Genes and Signaling Diversity in Brain Tumors.Single-cell analysis of phosphoinositide 3-kinase and phosphatase and tensin homolog activationAkt signaling pathway: a target for radiosensitizing human malignant glioma.
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Mechanisms of disease: the PI3K-Akt-PTEN signaling node--an intercept point for the control of angiogenesis in brain tumors.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mechanisms of disease: the PI3 ...... angiogenesis in brain tumors.
@en
Mechanisms of disease: the PI3 ...... angiogenesis in brain tumors.
@nl
type
label
Mechanisms of disease: the PI3 ...... angiogenesis in brain tumors.
@en
Mechanisms of disease: the PI3 ...... angiogenesis in brain tumors.
@nl
prefLabel
Mechanisms of disease: the PI3 ...... angiogenesis in brain tumors.
@en
Mechanisms of disease: the PI3 ...... angiogenesis in brain tumors.
@nl
P356
P1476
Mechanisms of disease: the PI3 ...... angiogenesis in brain tumors.
@en
P2093
Donald L Durden
Robert C Castellino
P2888
P304
P356
10.1038/NCPNEURO0661
P577
2007-12-01T00:00:00Z
P5875
P6179
1026269888