Inactivation of G-protein-coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis at midgestation through down-regulation of the ATF4 signaling pathway.
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R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5LGR4 and Its Role in Intestinal Protection and Energy MetabolismAdult mammalian stem cells: the role of Wnt, Lgr5 and R-spondinsThe R-spondin protein familyRegulation of bone formation and remodeling by G-protein-coupled receptor 48Lgr4 gene deficiency increases susceptibility and severity of dextran sodium sulfate-induced inflammatory bowel disease in miceLgr4-deficient mice showed premature differentiation of ureteric bud with reduced expression of Wnt effector Lef1 and Gata3Lgr4/Gpr48 negatively regulates TLR2/4-associated pattern recognition and innate immunity by targeting CD14 expressionThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsLgr4 protein deficiency induces ataxia-like phenotype in mice and impairs long term depression at cerebellar parallel fiber-Purkinje cell synapsesGlobin gene expression in correlation with G protein-related genes during erythroid differentiation.Gpr48 deficiency induces polycystic kidney lesions and renal fibrosis in mice by activating Wnt signal pathway.A comprehensive joint analysis of the long and short RNA transcriptomes of human erythrocytes.Multi-functional norrin is a ligand for the LGR4 receptor.Lgr4 in ocular development and glaucomaSingle ingestion of soy β-conglycinin induces increased postprandial circulating FGF21 levels exerting beneficial health effects.Lgr4 is a key regulator of prostate development and prostate stem cell differentiation.Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2.The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strengthEmerging role for leucine-rich repeat-containing G-protein-coupled receptors LGR5 and LGR4 in cancer stem cells.GPR48-Induced keratinocyte proliferation occurs through HB-EGF mediated EGFR transactivation.LGR4 is required for sequential molar development.Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivoONC201 selectively induces apoptosis in cutaneous T-cell lymphoma cells via activating pro-apoptotic integrated stress response and inactivating JAK/STAT and NF-κB pathways.LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells.Leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial-mesenchymal transition.LGR4 is required for the cell survival of the peripheral mesenchyme at the embryonic stages of nephrogenesis.Conditional knockout of Lgr4 leads to impaired ductal elongation and branching morphogenesis in mouse mammary glands.
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Inactivation of G-protein-coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis at midgestation through down-regulation of the ATF4 signaling pathway.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 October 2008
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Inactivation of G-protein-coup ...... of the ATF4 signaling pathway.
@en
Inactivation of G-protein-coupled receptor 48
@nl
type
label
Inactivation of G-protein-coup ...... of the ATF4 signaling pathway.
@en
Inactivation of G-protein-coupled receptor 48
@nl
prefLabel
Inactivation of G-protein-coup ...... of the ATF4 signaling pathway.
@en
Inactivation of G-protein-coupled receptor 48
@nl
P2093
P2860
P356
P1476
Inactivation of G-protein-coup ...... of the ATF4 signaling pathway.
@en
P2093
Baoxing Li
Huiping Song
Jinsheng Weng
Mingyao Liu
Weijia Luo
Zhiqiang Wang
P2860
P304
36687-36697
P356
10.1074/JBC.M800721200
P407
P577
2008-10-27T00:00:00Z