Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses. - Wikidata - awgldk - TriplyDB

Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.

Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.

http://www.wikidata.org/entity/Q37036482

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Signal regulatory protein alpha (SIRPalpha)/CD47 interaction and function Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD47 CD47 regulates bone mass and tumor metastasis to bone Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling Clinical lung xenotransplantation--what donor genetic modifications may be necessary?Activated CD47 regulates multiple vascular and stress responses: implications for acute kidney injury and its management Thrombospondins as key regulators of synaptogenesis in the central nervous system CD47 knockout mice exhibit improved recovery from spinal cord injury.The CD47-binding peptide of thrombospondin-1 induces defenestration of liver sinusoidal endothelial cells Amyloid-β inhibits No-cGMP signaling in a CD36- and CD47-dependent manner CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCγ1 activation: evidence from mice and humans Thrombospondin-1 and angiotensin II inhibit soluble guanylyl cyclase through an increase in intracellular calcium concentration.Cardiac CD47 drives left ventricular heart failure through Ca2+-CaMKII-regulated induction of HDAC3.Thrombospondin-2 therapy ameliorates experimental glomerulonephritis via inhibition of cell proliferation, inflammation, and TGF-beta activation.Thrombospondin-1 activation of signal-regulatory protein-α stimulates reactive oxygen species production and promotes renal ischemia reperfusion injury.Thrombospondin-1 is an inhibitor of pharmacological activation of soluble guanylate cyclase.Cellular, pharmacological, and biophysical evaluation of explanted lungs from a patient with sickle cell disease and severe pulmonary arterial hypertension Predictive model of thrombospondin-1 and vascular endothelial growth factor in breast tumor tissue Elevated postinjury thrombospondin 1-CD47 triggering aids differentiation of patients' defective inflammatory CD1a+dendritic cells.CD47(low) status on CD4 effectors is necessary for the contraction/resolution of the immune response in humans and mice.Thrombospondin-1 inhibits VEGF receptor-2 signaling by disrupting its association with CD47.Age-associated induction of cell membrane CD47 limits basal and temperature-induced changes in cutaneous blood flow.Disruption of thrombospondin-2 accelerates ischemic fracture healing.Up-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function.Heparan sulfate modification of the transmembrane receptor CD47 is necessary for inhibition of T cell receptor signaling by thrombospondin-1.CD47-independent effects mediated by the TSP-derived 4N1K peptide.Thrombospondin-1 regulates blood flow via CD47 receptor-mediated activation of NADPH oxidase 1.Matricellular proteins in cardiac adaptation and disease.CD47 Promotes Protective Innate and Adaptive Immunity in a Mouse Model of Disseminated Candidiasis.Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1.The matricellular protein thrombospondin-1 globally regulates cardiovascular function and responses to stress via CD47.Loss-of-function thrombospondin-1 mutations in familial pulmonary hypertension Molecular basis for the regulation of angiogenesis by thrombospondin-1 and -2.CD47 blockade reduces ischemia/reperfusion injury and improves survival in a rat liver transplantation model.Original insights on thrombospondin-1-related antireceptor strategies in cancer.Trauma patients' elevated tumor necrosis related apoptosis inducing ligand (TRAIL) contributes to increased T cell apoptosis.Secreted Thrombospondin-1 Regulates Macrophage Interleukin-1β Production and Activation through CD47.CD47 signaling pathways controlling cellular differentiation and responses to stress.Thrombospondin-1 and CD47 regulate blood pressure and cardiac responses to vasoactive stress Regulation of nitric oxide signalling by thrombospondin 1: implications for anti-angiogenic therapies

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P2860

Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.

http://www.wikidata.org/entity/Q37036482

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2008 nî lūn-bûn

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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Differential interactions of t ...... and ischemic injury responses.

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Differential interactions of t ...... and ischemic injury responses.

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Differential interactions of t ...... and ischemic injury responses.

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Differential interactions of t ...... and ischemic injury responses.

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Differential interactions of t ...... and ischemic injury responses.

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Differential interactions of t ...... and ischemic injury responses.

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P1476

Differential interactions of t ...... and ischemic injury responses

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P2093

Deane F Mosher

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Douglas S Annis

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Jeff S Isenberg

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Malgorzata Ptaszynska

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Michael L Pendrak

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William A Frazier

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P2860

Biophysical characterization of the signature domains of thrombospondin-4 and thrombospondin-2

Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake

Adhesion of human T cells to antigen-presenting cells through SIRPbeta2-CD47 interaction costimulates T-cell proliferation

Thrombospondin-4 and its variants: expression and differential effects on endothelial cells

Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner

Identification and characterization of thrombospondin-4, a new member of the thrombospondin gene family

Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior

Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis

Pro-adhesive and chemotactic activities of thrombospondin-1 for breast carcinoma cells are mediated by alpha3beta1 integrin and regulated by insulin-like growth factor-1 and CD98

Normal ligand binding and signaling by CD47 (integrin-associated protein) requires a long range disulfide bond between the extracellular and membrane-spanning domains

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1116-1125

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scholarly article

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10.1074/JBC.M804860200

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2

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284

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David D Roberts

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2008-11-11T00:00:00Z

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19004835

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2613617

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