SV40 small T antigen and PP2A phosphatase in cell transformation. - Wikidata - awgldk - TriplyDB

SV40 small T antigen and PP2A phosphatase in cell transformation.

SV40 small T antigen and PP2A phosphatase in cell transformation.

http://www.wikidata.org/entity/Q37063410

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Over expression of PPP2R2C inhibits human glioma cells growth through the suppression of mTOR pathway The broken "Off" switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillance Chk1 targeting reactivates PP2A tumor suppressor activity in cancer cells Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth.Human polyomaviruses in skin diseases.JC virus small T antigen binds phosphatase PP2A and Rb family proteins and is required for efficient viral DNA replication activity Physiological regulation of Akt activity and stability.Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer.Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer PP2A-mediated regulation of Ras signaling in G2 is essential for stable quiescence and normal G1 length.Endogenous Myc maintains the tumor microenvironment.EGF-induced EMT and invasiveness in serous borderline ovarian tumor cells: a possible step in the transition to low-grade serous carcinoma cells?Differential regulation of cutaneous oncoprotein HPVE6 by wtp53, mutant p53R248W and ΔNp63α is HPV type dependent.PP2A:B56{epsilon}, a substrate of caspase-3, regulates p53-dependent and p53-independent apoptosis during development.Viral oncogenes, noncoding RNAs, and RNA splicing in human tumor viruses Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.Blockade of the BAK hydrophobic groove by inhibitory phosphorylation regulates commitment to apoptosis.Comparative transcriptome profiling of an SV40-transformed human fibroblast (MRC5CVI) and its untransformed counterpart (MRC-5) in response to UVB irradiation.Therapeutic Re-Activation of Protein Phosphatase 2A in Acute Myeloid Leukemia Merkel cell polyomavirus-specific CD8⁺ and CD4⁺ T-cell responses identified in Merkel cell carcinomas and blood.CIP2A regulates cancer metabolism and CREB phosphorylation in non-small cell lung cancer.Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1.Nitric oxide and protein phosphatase 2A provide novel therapeutic opportunities in ER-negative breast cancer.Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling.Inhibition of Pten deficient Castration Resistant Prostate Cancer by Targeting of the SET - PP2A Signaling axis.A screen for modulators of large T antigen's ATPase activity uncovers novel inhibitors of Simian Virus 40 and BK virus replication.Systematic study of cis-antisense miRNAs in animal species reveals miR-3661 to target PPP2CA in human cells Novel polyomavirus associated with brain tumors in free-ranging raccoons, western United States Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis.Simian virus 40 T-antigen-mediated gene regulation in enterocytes is controlled primarily by the Rb-E2F pathway Functions of B56-containing PP2As in major developmental and cancer signaling pathways.Naturally occurring, tumor-specific, therapeutic proteins.Viruses and the fuel sensor: the emerging link between AMPK and virus replication.MYC degradation Molecular insight into the viral biology and clinical features of trichodysplasia spinulosa.All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase.A SMAP in the face for cancer.Inhibition of protein methylesterase 1 decreased cancerous phenotypes in endometrial adenocarcinoma cell lines and xenograft tumor models.Protein phosphatase 2A Cα regulates proliferation, migration, and metastasis of osteosarcoma cells.Bortezomib congeners induce apoptosis of hepatocellular carcinoma via CIP2A inhibition.

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SV40 small T antigen and PP2A phosphatase in cell transformation.

http://www.wikidata.org/entity/Q37063410

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on June 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

SV40 small T antigen and PP2A phosphatase in cell transformation.

@en

SV40 small T antigen and PP2A phosphatase in cell transformation.

@nl

type

label

SV40 small T antigen and PP2A phosphatase in cell transformation.

@en

SV40 small T antigen and PP2A phosphatase in cell transformation.

@nl

prefLabel

SV40 small T antigen and PP2A phosphatase in cell transformation.

@en

SV40 small T antigen and PP2A phosphatase in cell transformation.

@nl

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Cancer and Metastasis Reviews

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SV40 small T antigen and PP2A phosphatase in cell transformation.

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Anna A Sablina

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William C Hahn

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P2860

Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene

The vacuolating virus, S.V. 40

Simian virus 40 small tumor antigen inhibits dephosphorylation of protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation

Protein phosphatase 2A potentiates activity of promoters containing AP-1-binding elements.

Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity.

Tumors Induced in Hamsters by Injection of Rhesus Monkey Kidney Cell Extracts

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s10555-008-9116-0

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137-146

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scholarly article

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10.1007/S10555-008-9116-0

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2

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27

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