ErbB1/2 tyrosine kinase inhibitor mediates oxidative stress-induced apoptosis in inflammatory breast cancer cells.
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Inflammatory breast cancer tumor emboli express high levels of anti-apoptotic proteins: use of a quantitative high content and high-throughput 3D IBC spheroid assay to identify targeting strategiesReactive Oxygen Species-Mediated Mechanisms of Action of Targeted Cancer TherapyImmunologic targeting of FOXP3 in inflammatory breast cancer cells.Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death.Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer.Anoikis evasion in inflammatory breast cancer cells is mediated by Bim-EL sequestrationThe superoxide dismutase 1 3'UTR maintains high expression of the SOD1 gene in cancer cells: The involvement of the RNA-binding protein AUF-1.Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate.X-linked inhibitor of apoptosis protein mediates tumor cell resistance to antibody-dependent cellular cytotoxicity.Quantitative high-throughput efficacy profiling of approved oncology drugs in inflammatory breast cancer models of acquired drug resistance and re-sensitization.The role of antioxidants in the era of cardio‑oncology.Manganese superoxide dismutase, MnSOD and its mimicsBisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells.The future of biology in driving the field of hyperthermia.Lapatinib resistance in HER2+ cancers: latest findings and new concepts on molecular mechanisms.Differential behaviors of trastuzumab-sensitive and -resistant SKBR3 cells treated with menadione reveal the involvement of Notch1/Akt/FOXO1 signaling elements.Overexpression of HER-2/neu protein attenuates the oxidative systemic profile in women diagnosed with breast cancer.Potential for a novel manganese porphyrin compound as adjuvant canine lymphoma therapy.Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism.A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib.Pharmacological targeting of GLI1 inhibits proliferation, tumor emboli formation and in vivo tumor growth of inflammatory breast cancer cells.Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies.The Influence of Metabolism on Drug Response in Cancer
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P2860
ErbB1/2 tyrosine kinase inhibitor mediates oxidative stress-induced apoptosis in inflammatory breast cancer cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 May 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
ErbB1/2 tyrosine kinase inhibi ...... lammatory breast cancer cells.
@en
ErbB1/2 tyrosine kinase inhibi ...... lammatory breast cancer cells.
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type
label
ErbB1/2 tyrosine kinase inhibi ...... lammatory breast cancer cells.
@en
ErbB1/2 tyrosine kinase inhibi ...... lammatory breast cancer cells.
@nl
prefLabel
ErbB1/2 tyrosine kinase inhibi ...... lammatory breast cancer cells.
@en
ErbB1/2 tyrosine kinase inhibi ...... lammatory breast cancer cells.
@nl
P2093
P2860
P1476
ErbB1/2 tyrosine kinase inhibi ...... lammatory breast cancer cells.
@en
P2093
Gayathri R Devi
H Kim Lyerly
Ines Batinic-Haberle
Jennifer L Allensworth
Katherine M Aird
Mark W Dewhirst
P2860
P2888
P304
P356
10.1007/S10549-011-1568-1
P407
P577
2011-05-11T00:00:00Z