Stereospecific formation of interstrand carbinolamine DNA cross-links by crotonaldehyde- and acetaldehyde-derived alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine adducts in the 5'-CpG-3' sequence
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Acetaldehyde stimulates FANCD2 monoubiquitination, H2AX phosphorylation, and BRCA1 phosphorylation in human cells in vitro: implications for alcohol-related carcinogenesisPathways for repairing and tolerating the spectrum of oxidative DNA lesionsStereochemistry Modulates the Stability of Reduced Interstrand Cross-Links Arising from R - and S -α-CH 3 -γ-OH-1, N 2 -Propano-2‘-deoxyguanosine in the 5‘-CpG-3‘ DNA Sequence †The Stereochemistry of trans -4-Hydroxynonenal-Derived Exocyclic 1, N 2 -2′-Deoxyguanosine Adducts Modulates Formation of Interstrand Cross-Links in the 5′-CpG-3′ Sequence †Conformational Interconversion of the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S ) 1, N 2 -Deoxyguanosine Adduct When Mismatched with Deoxyadenosine in DNAFormation of a N 2 -dG: N 2 -dG Carbinolamine DNA Cross-link by the trans -4-Hydroxynonenal-Derived (6 S ,8 R ,11 S ) 1, N 2 -dG AdductRing-Opening of the γ-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4Methanesulfonyl ChlorideBiological properties of single chemical-DNA adducts: a twenty year perspectiveA novel link to base excision repair?Targeting aldehyde dehydrogenase 2: new therapeutic opportunities.Discovery of a series of aromatic lactones as ALDH1/2-directed inhibitors.Rescue of replication failure by Fanconi anaemia proteins.Chemical structure and properties of interstrand cross-links formed by reaction of guanine residues with abasic sites in duplex DNASite-specific synthesis of oligonucleotides containing malondialdehyde adducts of deoxyguanosine and deoxyadenosine via a postsynthetic modification strategy.The modulation of topoisomerase I-mediated DNA cleavage and the induction of DNA-topoisomerase I crosslinks by crotonaldehyde-derived DNA adducts.Analysis of crotonaldehyde- and acetaldehyde-derived 1,n(2)-propanodeoxyguanosine adducts in DNA from human tissues using liquid chromatography electrospray ionization tandem mass spectrometry.Formation of DNA-protein cross-links between gamma-hydroxypropanodeoxyguanosine and EcoRIChemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.DNA cross-link induced by trans-4-hydroxynonenal.Chemistry and structural biology of DNA damage and biological consequencesAcetaldehyde and the genome: beyond nuclear DNA adducts and carcinogenesis.What is the DNA repair defect underlying Fanconi anemia?Formation of deoxyguanosine cross-links from calf thymus DNA treated with acrolein and 4-hydroxy-2-nonenal.Molecular Mechanisms of Acetaldehyde-Mediated Carcinogenesis in Squamous Epithelium.Replication-coupled repair of crotonaldehyde/acetaldehyde-induced guanine-guanine interstrand cross-links and their mutagenicityRearrangement of the (6S,8R,11S) and (6R,8S,11R) exocyclic 1,N2-deoxyguanosine adducts of trans-4-hydroxynonenal to N2-deoxyguanosine cyclic hemiacetal adducts when placed complementary to cytosine in duplex DNA.Stereospecific formation of the (R)-gamma-hydroxytrimethylene interstrand N2-dG:N2-dG cross-link arising from the gamma-OH-1,N2-propano-2'-deoxyguanosine adduct in the 5'-CpG-3' DNA sequence.Interstrand DNA cross-links induced by alpha,beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources.Chemistry of Inflammation and DNA Damage: Biological Impact of Reactive Nitrogen Species
P2860
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P2860
Stereospecific formation of interstrand carbinolamine DNA cross-links by crotonaldehyde- and acetaldehyde-derived alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine adducts in the 5'-CpG-3' sequence
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on February 2006
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Stereospecific formation of in ...... ucts in the 5'-CpG-3' sequence
@en
Stereospecific formation of in ...... cts in the 5'-CpG-3' sequence.
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type
label
Stereospecific formation of in ...... ucts in the 5'-CpG-3' sequence
@en
Stereospecific formation of in ...... cts in the 5'-CpG-3' sequence.
@nl
prefLabel
Stereospecific formation of in ...... ucts in the 5'-CpG-3' sequence
@en
Stereospecific formation of in ...... cts in the 5'-CpG-3' sequence.
@nl
P2093
P2860
P356
P1476
Stereospecific formation of in ...... ucts in the 5'-CpG-3' sequence
@en
P2093
Andrew J Kurtz
Carmelo J Rizzo
Ivan D Kozekov
Jaison Jacob
Jarrod Smith
Markus Voehler
Michael P Stone
R Stephen Lloyd
Thomas M Harris
P2860
P304
P356
10.1021/TX050239Z
P577
2006-02-01T00:00:00Z