Increased cytoplasmic TARDBP mRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-43
about
Quantitative analysis of cryptic splicing associated with TDP-43 depletion.Drosophila lines with mutant and wild type human TDP-43 replacing the endogenous gene reveals phosphorylation and ubiquitination in mutant lines in the absence of viability or lifespan defects.Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALSSplicing factors act as genetic modulators of TDP-43 production in a new autoregulatory TDP-43 Drosophila model.Cleavage and polyadenylation: Ending the message expands gene regulation.Novel miR-b2122 regulates several ALS-related RNA-binding proteins.Robustness and Vulnerability of the Autoregulatory System That Maintains Nuclear TDP-43 Levels: A Trade-off Hypothesis for ALS Pathology Based on in Silico Data.TDP43 and RNA instability in amyotrophic lateral sclerosis.TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD.Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions.Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.The snowball effect of RNA binding protein dysfunction in amyotrophic lateral sclerosis.
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P2860
Increased cytoplasmic TARDBP mRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-43
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 02 June 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Increased cytoplasmic TARDBP m ...... ormal autoregulation of TDP-43
@en
Increased cytoplasmic TARDBP m ...... rmal autoregulation of TDP-43.
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type
label
Increased cytoplasmic TARDBP m ...... ormal autoregulation of TDP-43
@en
Increased cytoplasmic TARDBP m ...... rmal autoregulation of TDP-43.
@nl
prefLabel
Increased cytoplasmic TARDBP m ...... ormal autoregulation of TDP-43
@en
Increased cytoplasmic TARDBP m ...... rmal autoregulation of TDP-43.
@nl
P2093
P2860
P50
P356
P1476
Increased cytoplasmic TARDBP m ...... ormal autoregulation of TDP-43
@en
P2093
Akihide Koyama
Akio Yokoseki
Akiyoshi Kakita
Atsushi Shiga
Hitoshi Takahashi
Masatoyo Nishizawa
Misaki Koyama
Sachiko Hirokawa
Taisuke Kato
Yasuko Toyoshima
P2860
P304
P356
10.1093/NAR/GKW499
P407
P577
2016-06-02T00:00:00Z