Small-molecule inhibitors of Bcl-2 family proteins as therapeutic agents in cancer.
about
Cancer's Achilles' Heel: Apoptosis and Necroptosis to the RescueApogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo.Artemisia absinthium (AA): a novel potential complementary and alternative medicine for breast cancer.Current concepts of metastasis in melanoma.A peptide of SPARC interferes with the interaction between caspase8 and Bcl2 to resensitize chemoresistant tumors and enhance their regression in vivoSmall-Molecule and Peptide Inhibitors of the Pro-Survival Protein Mcl-1Oncogenic BRAF(V600E) inhibits BIM expression to promote melanoma cell survival.Bcl-2 inhibitors: small molecules with a big impact on cancer therapy.Induction of apoptosis in HeLa cells by chloroform fraction of seed extracts of Nigella sativa.Downregulation of Bcl-xL and Mcl-1 is sufficient to induce cell death in mesothelioma cells highly refractory to conventional chemotherapy.Phyllanthus amarus inhibits cell growth and induces apoptosis in Dalton's lymphoma ascites cells through activation of caspase-3 and downregulation of Bcl-2.In silico and in vitro elucidation of BH3 binding specificity toward Bcl-2Different forms of cell death induced by putative BCL2 inhibitors.
P2860
Q28066868-E0FE8FBC-2545-4B3C-AF39-8240DA0C62EBQ33930057-757E68C4-CBCC-4599-95E2-586CB4C944F8Q34252582-8611CDD2-F432-465E-9B0F-A0595E1B87C5Q34610427-D149A23D-3896-4F0B-A6E8-F2E0FC78833BQ35499905-8839F1C6-8235-405D-81D9-C6B586BE7876Q35876252-739FE0BC-5C5F-41CB-BF52-8ACD15DCFBFBQ37028555-56A80B4B-845C-4ED6-86B0-E88C70EBCCBAQ37275477-02F883B4-C3EF-4F0B-A2A9-08F6105EEF80Q37479706-A1658E0A-7633-4A04-A015-C6D70F761E8DQ39741953-BB7A6714-6F70-4B04-9720-8CCF20004164Q39882891-8B27903B-9701-4797-8FAF-B68FF90CD686Q41958792-BE23AF4E-EB06-4D49-B195-861D10E6387FQ43763736-5D3B6BC3-AB3B-4B69-A58F-76C53A078C07
P2860
Small-molecule inhibitors of Bcl-2 family proteins as therapeutic agents in cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Small-molecule inhibitors of Bcl-2 family proteins as therapeutic agents in cancer.
@en
Small-molecule inhibitors of Bcl-2 family proteins as therapeutic agents in cancer.
@nl
type
label
Small-molecule inhibitors of Bcl-2 family proteins as therapeutic agents in cancer.
@en
Small-molecule inhibitors of Bcl-2 family proteins as therapeutic agents in cancer.
@nl
prefLabel
Small-molecule inhibitors of Bcl-2 family proteins as therapeutic agents in cancer.
@en
Small-molecule inhibitors of Bcl-2 family proteins as therapeutic agents in cancer.
@nl
P1476
Small-molecule inhibitors of Bcl-2 family proteins as therapeutic agents in cancer
@en
P2093
Anshu Giri
Ramzi Mohammad
P356
10.2174/157489208783478676
P577
2008-01-01T00:00:00Z