Evolutionarily conserved amino acids that control TCR-MHC interaction.
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Coevolution of T-cell receptors with MHC and non-MHC ligandsStructural basis of metal hypersensitivityEpitope flexibility and dynamic footprint revealed by molecular dynamics of a pMHC-TCR complexHow a T Cell Receptor-like Antibody Recognizes Major Histocompatibility Complex-bound PeptideDistinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientationNatural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognitionA highly tilted binding mode by a self-reactive T cell receptor results in altered engagement of peptide and MHCStructure of a TCR with high affinity for self-antigen reveals basis for escape from negative selectionStructural insights into the binding of hepatitis B virus core peptide to HLA-A2 alleles: towards designing better vaccinesA Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR ConformersType II natural killer T cells use features of both innate-like and conventional T cells to recognize sulfatide self antigensTCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct MechanismsT-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergyT Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility ComplexA Role for Differential Variable Gene Pairing in Creating T Cell Receptors Specific for Unique Major Histocompatibility LigandsStructural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptorCrystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoireCrystal Structure of Vδ1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human γδ T CellsEffect of CDR3 Sequences and Distal V Gene Residues in Regulating TCR-MHC Contacts and Ligand SpecificityT cell receptor reversed polarity recognition of a self-antigen major histocompatibility complexTCR affinity for p/MHC formed by tumor antigens that are self-proteins: impact on efficacy and toxicityGermline-encoded amino acids in the alphabeta T-cell receptor control thymic selectionαβ T cell receptors that do not undergo major histocompatibility complex-specific thymic selection possess antibody-like recognition specificitiesMHC restriction is imposed on a diverse T cell receptor repertoire by CD4 and CD8 co-receptors during thymic selectionReconciling views on T cell receptor germline bias for MHCStructural insights into the editing of germ-line-encoded interactions between T-cell receptor and MHC class II by Vα CDR3T cells and their eons-old obsession with MHCLck availability during thymic selection determines the recognition specificity of the T cell repertoireThe molecular basis of TCR germline bias for MHC is surprisingly simpleCo-evolution of human leukocyte antigen (HLA) class I ligands with killer-cell immunoglobulin-like receptors (KIR) in a genetically diverse population of sub-Saharan AfricansT cell receptor bias for MHC: co-evolution or co-receptors?IMPIPS: the immune protection-inducing protein structure concept in the search for steric-electron and topochemical principles for complete fully-protective chemically synthesised vaccine developmentV genes in primates from whole genome sequencing data.How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoirePeriplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA.3D analysis of the TCR/pMHCII complex formation in monkeys vaccinated with the first peptide inducing sterilizing immunity against human malaria.An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role.Human-specific evolution and adaptation led to major qualitative differences in the variable receptors of human and chimpanzee natural killer cellsAntiviral immune responses: triggers of or triggered by autoimmunity?
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Evolutionarily conserved amino acids that control TCR-MHC interaction.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Evolutionarily conserved amino acids that control TCR-MHC interaction.
@en
Evolutionarily conserved amino acids that control TCR-MHC interaction.
@nl
type
label
Evolutionarily conserved amino acids that control TCR-MHC interaction.
@en
Evolutionarily conserved amino acids that control TCR-MHC interaction.
@nl
prefLabel
Evolutionarily conserved amino acids that control TCR-MHC interaction.
@en
Evolutionarily conserved amino acids that control TCR-MHC interaction.
@nl
P2860
P50
P1476
Evolutionarily conserved amino acids that control TCR-MHC interaction.
@en
P2093
Shaodong Dai
P2860
P304
P356
10.1146/ANNUREV.IMMUNOL.26.021607.090421
P577
2008-01-01T00:00:00Z