Transgenic mice overexpressing peroxiredoxin 6 show increased resistance to lung injury in hyperoxia. - Wikidata - awgldk - TriplyDB

Transgenic mice overexpressing peroxiredoxin 6 show increased resistance to lung injury in hyperoxia.

Transgenic mice overexpressing peroxiredoxin 6 show increased resistance to lung injury in hyperoxia.

http://www.wikidata.org/entity/Q37101092

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H2O2-dependent hyperoxidation of peroxiredoxin 6 (Prdx6) plays a role in cellular toxicity via up-regulation of iPLA2 activity Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models?Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications Reactive oxygen species in inflammation and tissue injury Measurement of protein sulfhydryls in response to cellular oxidative stress using gel electrophoresis and multiplexed fluorescent imaging analysis Peroxiredoxin 6 fails to limit phospholipid peroxidation in lung from Cftr-knockout mice subjected to oxidative challenge.Proteomic analysis of protective effects of polysaccharides from Salvia miltiorrhiza against immunological liver injury in mice.Cross-talk between pulmonary injury, oxidant stress, and gap junctional communication.Molecular cloning reveals nearly half of patients with Crohn's disease have an antibody to peroxiredoxin 6-like protein.Mouse Models of Oxidative Stress Indicate a Role for Modulating Healthy Aging.Genetic variation and gene expression in antioxidant related enzymes and risk of COPD: a systematic review.Of mice and men: comparative proteomics of bronchoalveolar fluid.Peroxiredoxin 6 differentially regulates acute and chronic cigarette smoke–mediated lung inflammatory response and injury.Deficiency of Prdx6 in lens epithelial cells induces ER stress response-mediated impaired homeostasis and apoptosis.The roles of peroxidase and phospholipase A2 activities of peroxiredoxin 6 in protecting pulmonary microvascular endothelial cells against peroxidative stress.Antioxidant peroxiredoxin 6 protein rescues toxicity due to oxidative stress and cellular hypoxia in vitro, and attenuates prion-related pathology in vivo Pulmonary administration of a water-soluble curcumin complex reduces severity of acute lung injury.Use of comparative proteomics to identify potential resistance mechanisms in cancer treatment.Inactivation of Peroxiredoxin 6 by the Pla Protease of Yersinia pestis.Proteomic analysis reveals the deregulation of inflammation-related proteins in acupuncture-treated rats with asthma onset Multiple roles of phospholipase A2 during lung infection and inflammation.A novel lysophosphatidylcholine acyl transferase activity is expressed by peroxiredoxin 6 Risk assessment, disease prevention and personalised treatments in breast cancer: is clinically qualified integrative approach in the horizon?A novel nontoxic inhibitor of the activation of NADPH oxidase reduces reactive oxygen species production in mouse lung.Mutation of Serine 32 to Threonine in Peroxiredoxin 6 Preserves Its Structure and Enzymatic Function but Abolishes Its Trafficking to Lamellar Bodies.Peptide targeting and imaging of damaged lung tissue in influenza-infected mice Peroxiredoxin 6 as an antioxidant enzyme: protection of lung alveolar epithelial type II cells from H2O2-induced oxidative stress.CFTR activity and mitochondrial function.Environmental toxicity, redox signaling and lung inflammation: the role of glutathione Contributions of nitric oxide synthase isoforms to pulmonary oxygen toxicity, local vs. mediated effects.Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A(2) activity.Adiponectin protects against hyperoxic lung injury and vascular leak Current perspectives of oxidative stress and its measurement in chronic obstructive pulmonary disease.Peroxiredoxin 6: a bifunctional enzyme with glutathione peroxidase and phospholipase A₂ activities.Novel roles of peroxiredoxins in inflammation, cancer and innate immunity.Phospholipase A(2) of peroxiredoxin 6 has a critical role in tumor necrosis factor-induced apoptosis.Peroxiredoxin 6 in the repair of peroxidized cell membranes and cell signaling.Differential expression and function of peroxiredoxin 1 and peroxiredoxin 6 in cancerous MCF-7 and noncancerous MCF-10A breast epithelial cells.Overexpression of Prdx6 and resistance to peroxide-induced death in Hepa1-6 cells: Prdx suppression increases apoptosis.

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Transgenic mice overexpressing peroxiredoxin 6 show increased resistance to lung injury in hyperoxia.

http://www.wikidata.org/entity/Q37101092

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article científic

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bilimsel makale

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scientific article published on 06 January 2006

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vedecký článok

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Transgenic mice overexpressing ...... e to lung injury in hyperoxia.

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Transgenic mice overexpressing ...... e to lung injury in hyperoxia.

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Transgenic mice overexpressing ...... e to lung injury in hyperoxia.

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Transgenic mice overexpressing ...... e to lung injury in hyperoxia.

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Transgenic mice overexpressing ...... e to lung injury in hyperoxia.

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Transgenic mice overexpressing ...... e to lung injury in hyperoxia.

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RCMB.2005-0333OC

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American Journal of Respiratory Cell and Molecular Biology

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Transgenic mice overexpressing ...... e to lung injury in hyperoxia.

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Aron B Fisher

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Sheldon I Feinstein

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Shelley A Phelan

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Yan Wang

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Yefim Manevich

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P2860

Characterization of a mammalian peroxiredoxin that contains one conserved cysteine

1-Cys peroxiredoxin overexpression protects cells against phospholipid peroxidation-mediated membrane damage

Increased sensitivity of homozygous Sod2 mutant mice to oxygen toxicity

Mice lacking catalase develop normally but show differential sensitivity to oxidant tissue injury

Mice with targeted mutation of peroxiredoxin 6 develop normally but are susceptible to oxidative stress

Phospholipid hydroperoxides are substrates for non-selenium glutathione peroxidase.

Cloning and expression of rat lung acidic Ca(2+)-independent PLA2 and its organ distribution.

A family of novel peroxidases, peroxiredoxins.

Hyperoxia-induced cell death in the lung--the correlation of apoptosis, necrosis, and inflammation.

Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia

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481-486

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scholarly article

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10.1165/RCMB.2005-0333OC

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4

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34

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16399955

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