The infected cell protein 0 of herpes simplex virus 1 dynamically interacts with proteasomes, binds and activates the cdc34 E2 ubiquitin-conjugating enzyme, and possesses in vitro E3 ubiquitin ligase activity.
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Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signalThe infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) associates with interferon regulatory factor 7 and consequently inhibits beta interferon promoter activityAbility of the human cytomegalovirus IE1 protein to modulate sumoylation of PML correlates with its functional activities in transcriptional regulation and infectivity in cultured fibroblast cellsPML residue lysine 160 is required for the degradation of PML induced by herpes simplex virus type 1 regulatory protein ICP0The degradation of promyelocytic leukemia and Sp100 proteins by herpes simplex virus 1 is mediated by the ubiquitin-conjugating enzyme UbcH5aThe molecular basis of herpes simplex virus latencyThe potential link between PML NBs and ICP0 in regulating lytic and latent infection of HSV-1Interaction of the equine herpesvirus 1 EICP0 protein with the immediate-early (IE) protein, TFIIB, and TBP may mediate the antagonism between the IE and EICP0 proteinsHSV-1 ICP0: paving the way for viral replicationKinesin-3 mediates axonal sorting and directional transport of alphaherpesvirus particles in neuronsHerpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions.ICP0 inhibits the decrease of HSV amplicon-mediated transgene expression.Herpes simplex virus 1-infected cell protein 0 contains two E3 ubiquitin ligase sites specific for different E2 ubiquitin-conjugating enzymesCharacterization of the novel E3 ubiquitin ligase encoded in exon 3 of herpes simplex virus-1-infected cell protein 0.Herpes simplex virus 1 mutant in which the ICP0 HUL-1 E3 ubiquitin ligase site is disrupted stabilizes cdc34 but degrades D-type cyclins and exhibits diminished neurotoxicityThe cellular localization pattern of Varicella-Zoster virus ORF29p is influenced by proteasome-mediated degradationNeither LAT nor open reading frame P mutations increase expression of spliced or intron-containing ICP0 transcripts in mouse ganglia latently infected with herpes simplex virusOverexpression of promyelocytic leukemia protein precludes the dispersal of ND10 structures and has no effect on accumulation of infectious herpes simplex virus 1 or its proteinsAn early regulatory function required in a cell type-dependent manner is expressed by the genomic but not the cDNA copy of the herpes simplex virus 1 gene encoding infected cell protein 0.Cullin E3 ligases and their rewiring by viral factorsHerpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes.Herpes simplex virus 1 precludes replenishment of the short-lived receptor of tumor necrosis factor alpha by virion host shutoff-dependent degradation of its mRNA.Replication of the herpes simplex virus genome: does it really go around in circles?Relationship of herpes simplex virus genome configuration to productive and persistent infections.Herpes simplex virus 1 ICP0 phosphorylation site mutants are attenuated for viral replication and impaired for explant-induced reactivation.Update on emerging antivirals for the management of herpes simplex virus infections: a patenting perspective.Role of ICP0 in the strategy of conquest of the host cell by herpes simplex virus 1The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture.Tumor viruses and cell signaling pathways: deubiquitination versus ubiquitinationCytoplasmic localized infected cell protein 0 (bICP0) encoded by bovine herpesvirus 1 inhibits β interferon promoter activity and reduces IRF3 (interferon response factor 3) protein levels.DNA sensing-independent inhibition of herpes simplex virus 1 replication by DAI/ZBP1Herpes simplex virus 1 has multiple mechanisms for blocking virus-induced interferon production.Herpes simplex virus downregulates secretory leukocyte protease inhibitor: a novel immune evasion mechanismThe zinc RING finger of bovine herpesvirus 1-encoded bICP0 protein is crucial for viral replication and virulence.Pyrrolidine dithiocarbamate inhibits herpes simplex virus 1 and 2 replication, and its activity may be mediated through dysregulation of the ubiquitin-proteasome system.Herpes simplex virus 1 gene expression is accelerated by inhibitors of histone deacetylases in rabbit skin cells infected with a mutant carrying a cDNA copy of the infected-cell protein no. 0.The differential requirement for cyclin-dependent kinase activities distinguishes two functions of herpes simplex virus type 1 ICP0.Regulation of the ORF61 promoter and ORF61 functions in varicella-zoster virus replication and pathogenesisPhosphorylation of eIF4E by Mnk-1 enhances HSV-1 translation and replication in quiescent cells.
P2860
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P2860
The infected cell protein 0 of herpes simplex virus 1 dynamically interacts with proteasomes, binds and activates the cdc34 E2 ubiquitin-conjugating enzyme, and possesses in vitro E3 ubiquitin ligase activity.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 July 2001
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The infected cell protein 0 of ...... E3 ubiquitin ligase activity.
@en
The infected cell protein 0 of ...... E3 ubiquitin ligase activity.
@nl
type
label
The infected cell protein 0 of ...... E3 ubiquitin ligase activity.
@en
The infected cell protein 0 of ...... E3 ubiquitin ligase activity.
@nl
prefLabel
The infected cell protein 0 of ...... E3 ubiquitin ligase activity.
@en
The infected cell protein 0 of ...... E3 ubiquitin ligase activity.
@nl
P2860
P356
P1476
The infected cell protein 0 of ...... o E3 ubiquitin ligase activity
@en
P2093
C Van Sant
R Hagglund
P2860
P304
P356
10.1073/PNAS.161283098
P407
P577
2001-07-10T00:00:00Z