LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction. - Wikidata - awgldk - TriplyDB

LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction.

LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction.

http://www.wikidata.org/entity/Q37124577

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Endogenous Leucine-Rich Repeat Kinase 2 Slows Synaptic Vesicle Recycling in Striatal Neurons.Disparate Postsynaptic Induction Mechanisms Ultimately Converge to Drive the Retrograde Enhancement of Presynaptic Efficacy.Development of a tissue-specific ribosome profiling approach in Drosophila enables genome-wide evaluation of translational adaptations.A postsynaptic Pi3K-CII dependent signaling controller for presynaptic homeostatic plasticity.Targeted kinase inhibition relieves slowness and tremor in a Drosophila model of LRRK2 Parkinson's disease.Acute Fasting Regulates Retrograde Synaptic Enhancement through a 4E-BP-Dependent Mechanism.Modeling Parkinson's Disease in Drosophila: What Have We Learned for Dominant Traits?Synapse-specific and compartmentalized expression of presynaptic homeostatic potentiation.

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LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction.

http://www.wikidata.org/entity/Q37124577

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 19 July 2016

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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LRRK2 regulates retrograde syn ...... ophila neuromuscular junction.

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LRRK2 regulates retrograde syn ...... ophila neuromuscular junction.

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LRRK2 regulates retrograde syn ...... ophila neuromuscular junction.

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LRRK2 regulates retrograde syn ...... ophila neuromuscular junction.

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prefLabel

LRRK2 regulates retrograde syn ...... ophila neuromuscular junction.

@en

LRRK2 regulates retrograde syn ...... ophila neuromuscular junction.

@nl

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Nature Communications

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LRRK2 regulates retrograde syn ...... ophila neuromuscular junction.

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A Pejmun Haghighi

http://www.w3.org/2001/XMLSchema#string

Grant Kauwe

http://www.w3.org/2001/XMLSchema#string

Jay Penney

http://www.w3.org/2001/XMLSchema#string

Kazuya Tsurudome

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Lindsay Gray

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Mario R Calderon

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P2860

Alzheimer mechanisms and therapeutic strategies

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

The Parkinson disease-linked LRRK2 protein mutation I2020T stabilizes an active state conformation leading to increased kinase activity

Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis

The R1441C mutation of LRRK2 disrupts GTP hydrolysis

LRRK2 kinase regulates synaptic morphology through distinct substrates at the presynaptic and postsynaptic compartments of the Drosophila neuromuscular junction

The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation

Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease

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12188

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scholarly article

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10.1038/NCOMMS12188

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7

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Nahum Sonenberg

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2016-07-19T00:00:00Z

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27432119

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4960312

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