The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis?
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Human ind1, an iron-sulfur cluster assembly factor for respiratory complex ISpatial correlation between brain aerobic glycolysis and amyloid-β (Aβ ) depositionMitochondrial Dysfunction in Alzheimer's Disease and the Rationale for Bioenergetics Based TherapiesBioenergetic dysfunction and inflammation in Alzheimer's disease: a possible connectionMitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic interventionHormesis in aging and neurodegeneration-a prodigy awaiting dissectionMitochondrial dysfunction: different routes to Alzheimer's disease therapyEdaravone guards dopamine neurons in a rotenone model for Parkinson's diseaseParkin-mediated mitophagy in mutant hAPP neurons and Alzheimer's disease patient brainsElevated mitochondrial oxidative stress impairs metabolic adaptations to exercise in skeletal musclePartial complex I deficiency due to the CNS conditional ablation of Ndufa5 results in a mild chronic encephalopathy but no increase in oxidative damage.Cytoskeletal pathologies of Alzheimer diseaseResting state functional connectivity in preclinical Alzheimer's diseaseBiomarker Validation for Aging: Lessons from mtDNA Heteroplasmy Analyses in Early Cancer Detection.Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease.An integrated pipeline for next-generation sequencing and annotation of mitochondrial genomes.Rapamycin increases mitochondrial efficiency by mtDNA-dependent reprogramming of mitochondrial metabolism in Drosophila.The road to rack and ruin: selecting deleterious mitochondrial DNA variantsMitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS).Mitochondrial DNA haplogroup distribution in Chaoshanese with and without myopia.Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations.Assessment of cytochrome C oxidase dysfunction in the substantia nigra/ventral tegmental area in schizophrenia.Metabolism control by the circadian clock and vice versa.The metabolic enhancer piracetam ameliorates the impairment of mitochondrial function and neurite outgrowth induced by beta-amyloid peptideDecrease in age-related tau hyperphosphorylation and cognitive improvement following vitamin D supplementation are associated with modulation of brain energy metabolism and redox state.Alzheimer's disease: diverse aspects of mitochondrial malfunctioning.When a theory of aging ages badly.Taking a "good" look at free radicals in the aging process.Friedreich ataxia: molecular mechanisms, redox considerations, and therapeutic opportunities.Acrolein as a novel therapeutic target for motor and sensory deficits in spinal cord injurySuperoxide dismutase mimics: chemistry, pharmacology, and therapeutic potentialLeft ventricular global transcriptional profiling in human end-stage dilated cardiomyopathy.Defects in mitochondrial axonal transport and membrane potential without increased reactive oxygen species production in a Drosophila model of Friedreich ataxiaAge-related mitochondrial changes after traumatic brain injuryMitochondrial bioenergetic alterations in mouse neuroblastoma cells infected with Sindbis virus: implications to viral replication and neuronal death.Mitochondrial protection attenuates inflammation-induced impairment of neurogenesis in vitro and in vivo.Methylene blue as a cerebral metabolic and hemodynamic enhancer.Neuronal MCP-1 mediates microglia recruitment and neurodegeneration induced by the mild impairment of oxidative metabolism.SOD2, the principal scavenger of mitochondrial superoxide, is dispensable for embryogenesis and imaginal tissue development but essential for adult survivalExposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans
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The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis?
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 09 April 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The mitochondrial impairment, ...... just an attractive hypothesis?
@en
The mitochondrial impairment, ...... just an attractive hypothesis?
@nl
type
label
The mitochondrial impairment, ...... just an attractive hypothesis?
@en
The mitochondrial impairment, ...... just an attractive hypothesis?
@nl
prefLabel
The mitochondrial impairment, ...... just an attractive hypothesis?
@en
The mitochondrial impairment, ...... just an attractive hypothesis?
@nl
P2860
P1476
The mitochondrial impairment, ...... just an attractive hypothesis?
@en
P2093
Carlos T Moraes
P2860
P304
P356
10.1016/J.TINS.2008.02.008
P577
2008-04-09T00:00:00Z