Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations.
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Mitochondrial DNA backgrounds might modulate diabetes complications rather than T2DM as a wholeThimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNAThe role of oxidative stress in Parkinson's diseaseAgeing and Parkinson's disease: why is advancing age the biggest risk factor?Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration.Mitochondrial DNA mutations affect calcium handling in differentiated neurons.Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich's ataxia.Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice.Heterogeneous patterns of tissue injury in NARP syndromeA method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans.Cerebellar ataxia in patients with mitochondrial DNA disease: a molecular clinicopathological study.Effects of inhibiting CoQ10 biosynthesis with 4-nitrobenzoate in human fibroblasts.Dopamine induced neurodegeneration in a PINK1 model of Parkinson's disease.Reactive oxygen species, oxidative stress, and cell death correlate with level of CoQ10 deficiency.Neuronal and astrocyte dysfunction diverges from embryonic fibroblasts in the Ndufs4fky/fky mouse.Sensory neuropathy attributable to loss of Bcl-w.Stable differences in intrinsic mitochondrial membrane potential of tumor cell subpopulations reflect phenotypic heterogeneity.Mechanism of oxidative stress in neurodegeneration.OXPHOS mutations and neurodegenerationMitochondrial disease: mtDNA and protein segregation mysteries in iPSCsNrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration.Mitochondrial mutations: newly discovered players in neuronal degeneration.Metabolic response to glatiramer acetate therapy in multiple sclerosis patients.Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration.Unravelling mitochondrial pathways to Parkinson's disease.Mitochondrial DNA mutations and cognition: a case-series report.Autopsy case of the C12orf65 mutation in a patient with signs of mitochondrial dysfunction.Human neuronal coenzyme Q10 deficiency results in global loss of mitochondrial respiratory chain activity, increased mitochondrial oxidative stress and reversal of ATP synthase activity: implications for pathogenesis and treatment.Concise Review: Induced Pluripotent Stem Cell-Based Drug Discovery for Mitochondrial Disease.'Mitochondrial energy imbalance and lipid peroxidation cause cell death in Friedreich's ataxia'.Nrf2 regulates ROS production by mitochondria and NADPH oxidaseAggregated α-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons.Mitochondrial dysfunction in Parkinsonian mesenchymal stem cells impairs differentiation.Mutation or knock-down of 17β-hydroxysteroid dehydrogenase type 10 cause loss of MRPP1 and impaired processing of mitochondrial heavy strand transcripts.
P2860
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P2860
Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations.
@ast
Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations.
@en
type
label
Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations.
@ast
Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations.
@en
prefLabel
Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations.
@ast
Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations.
@en
P2093
P2860
P50
P356
P1433
P1476
Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations.
@en
P2093
Denise M Kirby
Douglass M Turnbull
José Antonio Enriquez
Rebeca Acin-Perez
Robert N Lightowlers
P2860
P304
P356
10.1093/BRAIN/AWQ015
P407
P577
2010-02-15T00:00:00Z