Nitrated {alpha}-synuclein-induced alterations in microglial immunity are regulated by CD4+ T cell subsets
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Central Nervous System-Peripheral Immune System Dialogue in Neurological Disorders: Possible Application of Neuroimmunology in UrologyROS and brain diseases: the good, the bad, and the uglyVaccination strategies for Parkinson disease: induction of a swift attack or raising tolerance?Neuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunityRegulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease.Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants.Microglia acquire distinct activation profiles depending on the degree of alpha-synuclein neuropathology in a rAAV based model of Parkinson's disease.Nitrated alpha-synuclein induces the loss of dopaminergic neurons in the substantia nigra of rats.Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic interventionControl of neuroinflammation as a therapeutic strategy for amyotrophic lateral sclerosis and other neurodegenerative disordersFunctional proteomic analysis for regulatory T cell surveillance of the HIV-1-infected macrophage.Chemically modified peptides based on the membrane-proximal external region of the HIV-1 envelope induce high-titer, epitope-specific nonneutralizing antibodies in rabbitsAdaptive immune regulation of glial homeostasis as an immunization strategy for neurodegenerative diseasesT-Lymphocyte Deficiency Exacerbates Behavioral Deficits in the 6-OHDA Unilateral Lesion Rat Model for Parkinson's Disease.The endotoxin-induced neuroinflammation model of Parkinson's disease.Blood dendritic cell frequency declines in idiopathic Parkinson's disease and is associated with motor symptom severityDual destructive and protective roles of adaptive immunity in neurodegenerative disorders.Effect of thymic stimulation of CD4+ T cell expansion on disease onset and progression in mutant SOD1 mice.The acute inflammatory response to intranigral α-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation.Inflammatory effects of highly pathogenic H5N1 influenza virus infection in the CNS of mice.Increased α-synuclein phosphorylation and nitration in the aging primate substantia nigra.Inhibition of Calpain Activation Protects MPTP-Induced Nigral and Spinal Cord Neurodegeneration, Reduces Inflammation, and Improves Gait Dynamics in Mice.Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy.Taking the Perspective that a Depressive State Reflects Inflammation: Implications for the Use of AntidepressantsA Perspective on Roles Played by Innate and Adaptive Immunity in the Pathobiology of Neurodegenerative DisordersChronic reactive gliosis following regulatory T cell depletion during acute MCMV encephalitis.Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survivalNeuroinflammation in Parkinson's disease.CD 4+ T cells in the pathobiology of neurodegenerative disorders.Dopaminergic Receptors on CD4+ T Naive and Memory Lymphocytes Correlate with Motor Impairment in Patients with Parkinson's Disease.Proteomic studies of nitrated alpha-synuclein microglia regulation by CD4+CD25+ T cells.GM-CSF induces neuroprotective and anti-inflammatory responses in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxicated mice.Neurodegenerative disorders and nanoformulated drug development.A coat of many colors: neuroimmune crosstalk in human immunodeficiency virus infection.T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening?ALS patients' regulatory T lymphocytes are dysfunctional, and correlate with disease progression rate and severity.Activated immune cells in Parkinson's disease.Do PPAR-Gamma Agonists Have a Future in Parkinson's Disease Therapy?Modulating microglia activity with PPAR-γ agonists: a promising therapy for Parkinson's disease?Oxidative and nitrative alpha-synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathies.
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Nitrated {alpha}-synuclein-induced alterations in microglial immunity are regulated by CD4+ T cell subsets
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Nitrated {alpha}-synuclein-ind ...... gulated by CD4+ T cell subsets
@en
Nitrated {alpha}-synuclein-ind ...... ulated by CD4+ T cell subsets.
@nl
type
label
Nitrated {alpha}-synuclein-ind ...... gulated by CD4+ T cell subsets
@en
Nitrated {alpha}-synuclein-ind ...... ulated by CD4+ T cell subsets.
@nl
altLabel
Nitrated α-Synuclein-Induced A ...... gulated by CD4+ T Cell Subsets
@en
prefLabel
Nitrated {alpha}-synuclein-ind ...... gulated by CD4+ T cell subsets
@en
Nitrated {alpha}-synuclein-ind ...... ulated by CD4+ T cell subsets.
@nl
P2093
P2860
P356
P1476
Nitrated {alpha}-synuclein-ind ...... gulated by CD4+ T cell subsets
@en
P2093
Ashley D Reynolds
David K Stone
Howard E Gendelman
R Lee Mosley
P2860
P304
P356
10.4049/JIMMUNOL.0803982
P4011
850c20e2936f48829b017b65706a67dc70bc197f
P407
P577
2009-04-01T00:00:00Z