Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.
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Frizzled7: A Promising Achilles' Heel for Targeting the Wnt Receptor Complex to Treat CancerChronic inflammation and the development of malignancy in the GI tractAdaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer.The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis.A novel anti-cancer agent Icaritin suppresses hepatocellular carcinoma initiation and malignant growth through the IL-6/Jak2/Stat3 pathway.Randomized, Double-Blind, Phase II Study of Ruxolitinib or Placebo in Combination With Capecitabine in Patients With Metastatic Pancreatic Cancer for Whom Therapy With Gemcitabine Has Failed.MLLT11/AF1q boosts oncogenic STAT3 activity through Src-PDGFR tyrosine kinase signaling.Constitutive gp130 activation rapidly accelerates the transformation of human hepatocytes via an impaired oxidative stress responseLoss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo.Bazedoxifene as a Novel GP130 Inhibitor for Pancreatic Cancer Therapy.The potential role of liver stem cells in initiation of primary liver cancer.Wnt is necessary for mesenchymal to epithelial transition in colorectal cancer cells.Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5(+) stem cellsHIF-3α1 promotes colorectal tumor cell growth by activation of JAK-STAT3 signaling.Interleukin-17A-promoted MSC2 polarization related with new bone formation of ankylosing spondylitis.Defining key concepts of intestinal and epithelial cancer biology through the use of mouse models.Inflammation and Colorectal Cancer.Reg3g Promotes Pancreatic Carcinogenesis in a Murine Model of Chronic Pancreatitis.Wnt Signalling in Gastrointestinal Epithelial Stem Cells.STAT3 exacerbates survival of cancer stem-like tumorspheres in EGFR-positive colorectal cancers: RNAseq analysis and therapeutic screening
P2860
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P2860
Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Partial inhibition of gp130-Ja ...... tumor growth and regeneration.
@en
type
label
Partial inhibition of gp130-Ja ...... tumor growth and regeneration.
@en
prefLabel
Partial inhibition of gp130-Ja ...... tumor growth and regeneration.
@en
P2093
P2860
P50
P1433
P1476
Partial inhibition of gp130-Ja ...... tumor growth and regeneration
@en
P2093
Antony W Burgess
David G Kirsch
Dennis Huszar
Elizabeth Vincan
Emma Stuart
Francesca Walker
Hui-Hua Zhang
Jordane Malaterre
Maree Faux
Michael Buchert
P2860
P356
10.1126/SCISIGNAL.2005411
P50
P577
2014-09-30T00:00:00Z