The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse.
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Conditional deletion of neuronal cyclin-dependent kinase 5 in developing forebrain results in microglial activation and neurodegeneration.Biomarkers in Alzheimer's disease: past, present and future.Pathological implications of cell cycle re-entry in Alzheimer disease.Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis.Increased mRNA Levels of TCF7L2 and MYC of the Wnt Pathway in Tg-ArcSwe Mice and Alzheimer's Disease Brain.CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease.The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies.Early induction of c-Myc is associated with neuronal cell death.Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death.Inhibition of Bax protects neuronal cells from oligomeric Aβ neurotoxicityBrain Transcriptomic Response to Social Eavesdropping in Zebrafish (Danio rerio).Differential DNA Methylation of MicroRNA Genes in Temporal Cortex from Alzheimer's Disease Individuals.Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration.Control of vertebrate development by MYCEvidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease.All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's diseaseThe neuronal cell cycle as a mechanism of pathogenesis in Alzheimer's disease.Neuronal models for studying tau pathology.c-Myc induction of programmed cell death may contribute to carcinogenesis: a perspective inspired by several concepts of chemical carcinogenesis.Cell cycle reactivation in mature neurons: a link with brain plasticity, neuronal injury and neurodegenerative diseases?Cell cycle deregulation in the neurons of Alzheimer's disease.DNA topoisomerase IIβ as a molecular switch in neural differentiation of mesenchymal stem cells.Physiological and pathophysiological functions of cell cycle proteins in post-mitotic neurons: implications for Alzheimer's diseaseOxidative Stress and Aberrant Cell Cycle in Alzheimer's Disease Lymphocytes: Diagnostic Prospects.Abortive cell cycle events in the brains of scrapie-infected hamsters with remarkable decreases of PLK3/Cdc25C and increases of PLK1/cyclin B1.SRPK2 phosphorylates tau and mediates the cognitive defects in Alzheimer's disease.Ethanol-induced changes in poly (ADP ribose) polymerase and neuronal developmental gene expression.Efficacy of cyclin dependent kinase 4 inhibitors as potent neuroprotective agents against insults relevant to Alzheimer's disease.MicroRNA-455-3p as a potential peripheral biomarker for Alzheimer's disease.Distinct chronology of neuronal cell cycle re-entry and tau pathology in the 3xTg-AD mouse model and Alzheimer's disease patients.The Potential Protective Effect of Curcumin on Amyloid-β-42 Induced Cytotoxicity in HT-22 Cells.
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The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 22 January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The neuronal expression of MYC ...... e in a novel transgenic mouse.
@en
The neuronal expression of MYC ...... e in a novel transgenic mouse.
@nl
type
label
The neuronal expression of MYC ...... e in a novel transgenic mouse.
@en
The neuronal expression of MYC ...... e in a novel transgenic mouse.
@nl
prefLabel
The neuronal expression of MYC ...... e in a novel transgenic mouse.
@en
The neuronal expression of MYC ...... e in a novel transgenic mouse.
@nl
P2093
P2860
P50
P1476
The neuronal expression of MYC ...... e in a novel transgenic mouse.
@en
P2093
Akihiko Nunomura
Dean W Felsher
Gemma Casadesus
Hyoung-gon Lee
Robert B Petersen
Rudy J Castellani
Sandy L Richardson
P2860
P304
P356
10.2353/AJPATH.2009.080583
P407
P577
2009-01-22T00:00:00Z