BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease - Wikidata - awgldk - TriplyDB

BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

http://www.wikidata.org/entity/Q35793508

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The excitotoxin quinolinic acid induces tau phosphorylation in human neurons Repair of oxidative DNA damage, cell-cycle regulation and neuronal death may influence the clinical manifestation of Alzheimer's disease.Induction of neuro-protective/regenerative genes in stem cells infiltrating post-ischemic brain tissue.Differential network analyses of Alzheimer's disease identify early events in Alzheimer's disease pathology Pathological implications of cell cycle re-entry in Alzheimer disease.Evidence for induction of the ornithine transcarbamylase expression in Alzheimer's disease.Cell cycle checkpoint abnormalities during dementia: A plausible association with the loss of protection against oxidative stress in Alzheimer's disease [corrected].Beta-amyloid increases the expression level of ATBF1 responsible for death in cultured cortical neurons.BRCA1 silencing is associated with failure of DNA repairing in retinal neurocytes Inhibition of Polo-like kinase 1 reduces beta-amyloid-induced neuronal cell death in Alzheimer's disease.Brca1 is expressed in human microglia and is dysregulated in human and animal model of ALS.Oxidative stress response and Nrf2 signaling in aging.DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice.Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease.HIV-infected macrophages mediate neuronal apoptosis through mitochondrial glutaminase The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse.Global hypermethylation in fetal cortex of Down syndrome due to DNMT3L overexpression.Tumorigenesis and neurodegeneration: two sides of the same coin?Cell cycle deregulation in the neurons of Alzheimer's disease.Cell cycle proteins in brain in mild cognitive impairment: insights into progression to Alzheimer disease.Caffeine modulates tau phosphorylation and affects Akt signaling in postmitotic neurons.Loss of the chromatin regulator MRG15 limits neural stem/progenitor cell proliferation via increased expression of the p21 Cdk inhibitor.Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer's disease.Distinct chronology of neuronal cell cycle re-entry and tau pathology in the 3xTg-AD mouse model and Alzheimer's disease patients.U1 snRNP Alteration and Neuronal Cell Cycle Reentry in Alzheimer Disease.Brca1 Is Upregulated by 5-Aza-CdR and Promotes DNA Repair and Cell Survival, and Inhibits Neurite Outgrowth in Rat Retinal Neurons.Repositioning Microtubule Stabilizing Drugs for Brain Disorders

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BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

http://www.wikidata.org/entity/Q35793508

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

2007年论文

@zh

2007年论文

@zh-cn

name

BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

@ast

BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

@en

type

label

BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

@ast

BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

@en

prefLabel

BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

@ast

BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

@en

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P1433

International Journal of Medical Sciences

P1476

BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

@en

P2093

André Delacourte

http://www.w3.org/2001/XMLSchema#string

Arun K Raina

http://www.w3.org/2001/XMLSchema#string

Hyoung-gon Lee

http://www.w3.org/2001/XMLSchema#string

Olga Aprelikova

http://www.w3.org/2001/XMLSchema#string

Teresa A Evans

http://www.w3.org/2001/XMLSchema#string

P2860

Phosphorylated BRCA1 is predominantly located in the nucleus and mitochondria

Tumor suppressor gene BRCA-1 is expressed by embryonic and adult neural stem cells and involved in cell proliferation

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

Telomeres and telomerase in Alzheimer's disease: epiphenomena or a new focus for therapeutic strategy?

Elevated expression of p21ras is an early event in Alzheimer's disease and precedes neurofibrillary degeneration.

BRCA1 is associated with the centrosome during mitosis.

Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains.

Evidence for a transcriptional activation function of BRCA1 C-terminal region.

Are p27 and p21 cytoplasmic oncoproteins?

P304

140-145

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scholarly article

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10.7150/IJMS.4.140

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3

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4

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Mark Anthony Smith

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2007-05-12T00:00:00Z

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17505559

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Alzheimer's disease

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1868658

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