Adenovirus induction of IRF3 occurs through a binary trigger targeting Jun N-terminal kinase and TBK1 kinase cascades and type I interferon autocrine signaling.
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Adenovirus membrane penetration: Tickling the tail of a sleeping dragonUnabated adenovirus replication following activation of the cGAS/STING-dependent antiviral response in human cells.The challenge for gene therapy: innate immune response to adenovirusesThe genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver.Adenovirus sequesters phosphorylated STAT1 at viral replication centers and inhibits STAT dephosphorylation.Molecular characterization, expression of chicken TBK1 gene and its effect on IRF3 signaling pathwayAmplification of JNK signaling is necessary to complete the murine gammaherpesvirus 68 lytic replication cycle.Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response.IRF3 and ERK MAP-kinases control nitric oxide production from macrophages in response to poly-I:C.A new link between virus cell entry and inflammation: adenovirus interaction with integrins induces specific proinflammatory responses.Innate immunity to adenovirus.Adenovirus-triggered innate signalling pathways.Adenovirus type 5 rupture of lysosomes leads to cathepsin B-dependent mitochondrial stress and production of reactive oxygen species.Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β.Adenovirus detection by the cGAS/STING/TBK1 DNA sensing cascade.Cell-specific regulation of nucleic acid sensor cascades: a controlling interest in the antiviral response.Sensing adenovirus infection: activation of interferon regulatory factor 3 in RAW 264.7 cells.Lysosomal localization and mechanism of membrane penetration influence nonenveloped virus activation of the NLRP3 inflammasome.Adenovirus membrane penetration activates the NLRP3 inflammasome.S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3.FX and host defense evasion tactics by adenovirus.Partial protection against SIV challenge by vaccination of adenovirus and MVA vectors in rhesus monkeys.
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P2860
Adenovirus induction of IRF3 occurs through a binary trigger targeting Jun N-terminal kinase and TBK1 kinase cascades and type I interferon autocrine signaling.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Adenovirus induction of IRF3 o ...... nterferon autocrine signaling.
@en
Adenovirus induction of IRF3 o ...... nterferon autocrine signaling.
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type
label
Adenovirus induction of IRF3 o ...... nterferon autocrine signaling.
@en
Adenovirus induction of IRF3 o ...... nterferon autocrine signaling.
@nl
prefLabel
Adenovirus induction of IRF3 o ...... nterferon autocrine signaling.
@en
Adenovirus induction of IRF3 o ...... nterferon autocrine signaling.
@nl
P2093
P2860
P356
P1433
P1476
Adenovirus induction of IRF3 o ...... nterferon autocrine signaling.
@en
P2093
Erik Falck-Pedersen
Marcelo Nociari
Mary Murphy
P2860
P304
P356
10.1128/JVI.02591-08
P407
P577
2009-02-11T00:00:00Z