The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications.
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Proapoptotic kinase MST2 coordinates signaling crosstalk between RASSF1A, Raf-1, and AktFoxM1, a critical regulator of oxidative stress during oncogenesisThe oncoprotein HBXIP uses two pathways to up-regulate S100A4 in promotion of growth and migration of breast cancer cellsTargeting mTOR for the treatment of AML. New agents and new directionsCoactivation of AKT and β-catenin in mice rapidly induces formation of lipogenic liver tumorsThe MST/Hippo Pathway and Cell Death: A Non-Canonical AffairRoles of PTEN with DNA Repair in Parkinson's DiseaseMicroRNAs in multiple myeloma and related bone diseaseMolecular characterizations of glioblastoma, targeted therapy, and clinical results to dateChronic infection by Leishmania amazonensis mediated through MAPK ERK mechanismsTargeted therapies in development for non-small cell lung cancerRictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1Discovery of 4-Amino-1-(7 H -pyrrolo[2,3- d ]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt)Loss of PTEN is not associated with poor survival in newly diagnosed glioblastoma patients of the temozolomide era.Neuraminidase-1: a novel therapeutic target in multistage tumorigenesisRecent development of ATP-competitive small molecule phosphatidylinostitol-3-kinase inhibitors as anticancer agentsStress responses from the endoplasmic reticulum in cancerPTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastomaGlutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinomaCaveolin-1 regulates endothelial adhesion of lung cancer cells via reactive oxygen species-dependent mechanismInsulin-modulated Akt subcellular localization determines Akt isoform-specific signaling.Anticancer activities of pterostilbene-isothiocyanate conjugate in breast cancer cells: involvement of PPARγThe landscape of cancer genes and mutational processes in breast cancerPrediction of functionally significant single nucleotide polymorphisms [SNPs] in PTEN tumor suppressor gene: An in silico approach.MUFFINN: cancer gene discovery via network analysis of somatic mutation data.Bimodal regulation of FoxO3 by AKT and 14-3-3Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activitiesMolecular fingerprinting of radiation resistant tumors: can we apprehend and rehabilitate the suspects?Role of the PEBP4 protein in the development and metastasis of gastric cancer.PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in miceLevels of active tyrosine kinase receptor determine the tumor response to ZalypsisChemopreventive potential of curcumin in prostate cancerPhysiological regulation of Akt activity and stability.Nicotinamide N-methyltransferase induces cellular invasion through activating matrix metalloproteinase-2 expression in clear cell renal cell carcinoma cells.MicroRNA-216a promotes the metastasis and epithelial-mesenchymal transition of ovarian cancer by suppressing the PTEN/AKT pathway.β-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt PathwaycAMP/CREB-mediated transcriptional regulation of ectonucleoside triphosphate diphosphohydrolase 1 (CD39) expression.Induction of ATM/ATR pathway combined with Vγ2Vδ2 T cells enhances cytotoxicity of ovarian cancer cellsOpposite effects of HIV-1 p17 variants on PTEN activation and cell growth in B cells.TCR-induced Akt serine 473 phosphorylation is regulated by protein kinase C-alpha
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The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications.
@en
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications.
@nl
type
label
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications.
@en
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications.
@nl
prefLabel
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications.
@en
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications.
@nl
P50
P1476
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications.
@en
P304
P356
10.2174/156800908784293659
P577
2008-05-01T00:00:00Z