Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential
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Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironmentA Fluorescence-Guided Laser Ablation System for Removal of Residual Cancer in a Mouse Model of Soft Tissue Sarcoma.Co-depletion of cathepsin B and uPAR induces G0/G1 arrest in glioma via FOXO3a mediated p27 upregulation.Regulation of TGF-β1-driven differentiation of human lung fibroblasts: emerging roles of cathepsin B and cystatin C.Deleterious effect of oltipraz on extrahepatic cholestasis in bile duct-ligated mice.Cathepsin L and B as Potential Markers for Liver Fibrosis: Insights From Patients and Experimental Models.Acidic sphingomyelinase controls hepatic stellate cell activation and in vivo liver fibrogenesisA possible contribution of altered cathepsin B expression to the development of skin sclerosis and vasculopathy in systemic sclerosisMolecular imaging of Cathepsin E-positive tumors in mice using a novel protease-activatable fluorescent probe.Angiogenin secretion from hepatoma cells activates hepatic stellate cells to amplify a self-sustained cycle promoting liver cancer.Urinary candidate biomarker discovery in a rat unilateral ureteral obstruction model.Cathepsin B overexpression due to acid sphingomyelinase ablation promotes liver fibrosis in Niemann-Pick disease.Etiopathogenesis of nonalcoholic steatohepatitis: role of obesity, insulin resistance and mechanisms of hepatotoxicity.Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease.A Comparative Study of Cathepsin D Expression in Peripheral and Central Giant Cell Granuloma of the Jaws by Immunohistochemistry Technique.Cathepsin S-mediated fibroblast trans-differentiation contributes to left ventricular remodelling after myocardial infarction.Mechanisms of fibrosis in acute liver failure.Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation.Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells.The tumor microenvironment in hepatocellular carcinoma: current status and therapeutic targets.Lysosomal cholesterol accumulation: driver on the road to inflammation during atherosclerosis and non-alcoholic steatohepatitis.Mitochondrial cholesterol accumulation in alcoholic liver disease: Role of ASMase and endoplasmic reticulum stress.The Role of Ceramide in the Pathogenesis of Alcoholic Liver Disease.New role and molecular mechanism of Gadd45a in hepatic fibrosis.Ileal FGF15 contributes to fibrosis-associated hepatocellular carcinoma development.Side population in LX2 cells decreased by transforming growth factor-β.Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis.Cathepsin B deficiency attenuates cardiac remodeling in response to pressure overload via TNF-α/ASK1/JNK pathway.ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis.Treatment with CA-074Me, a Cathepsin B inhibitor, reduces lung interstitial inflammation and fibrosis in a rat model of polymyositis.Enhanced activity of lysosomal proteases in activated rat hepatic stellate cells is associated with a concomitant increase in the number of the mannose-6-phosphate/insulin-like growth factor II receptor.Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB2 receptor-deficient mice and decreased in CB1 receptor knockouts.Epithelial cell-derived cytokines CST3 and GDF15 as potential therapeutics for pulmonary fibrosis.Differential Role of Cathepsins S and B In Hepatic APC-Mediated NKT Cell Activation and Cytokine Secretion.
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P2860
Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Cathepsins B and D drive hepat ...... ote their fibrogenic potential
@en
Cathepsins B and D drive hepat ...... te their fibrogenic potential.
@nl
type
label
Cathepsins B and D drive hepat ...... ote their fibrogenic potential
@en
Cathepsins B and D drive hepat ...... te their fibrogenic potential.
@nl
prefLabel
Cathepsins B and D drive hepat ...... ote their fibrogenic potential
@en
Cathepsins B and D drive hepat ...... te their fibrogenic potential.
@nl
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P50
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P1433
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Cathepsins B and D drive hepat ...... ote their fibrogenic potential
@en
P2093
Núria Tarrats
P2860
P304
P356
10.1002/HEP.22753
P407
P577
2009-04-01T00:00:00Z