Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity - Wikidata - awgldk - TriplyDB

Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity

Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity

http://www.wikidata.org/entity/Q37162234

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Complex Coordination of Cell Plasticity by a PGC-1α-controlled Transcriptional Network in Skeletal Muscle Differential regulation of PGC-1alpha expression in rat liver and skeletal muscle in response to voluntary running Mex3c mutation reduces adiposity and increases energy expenditure PGC-1alpha regulation by exercise training and its influences on muscle function and insulin sensitivity.PGC-1α overexpression exacerbates β-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease.Maintaining PGC-1α expression following pressure overload-induced cardiac hypertrophy preserves angiogenesis but not contractile or mitochondrial function.NHE1 deficiency in liver: implications for non-alcoholic fatty liver disease.PGC-1α and exercise in the control of body weight.Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation.Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect.Dietary quercetin supplementation in mice increases skeletal muscle PGC1α expression, improves mitochondrial function and attenuates insulin resistance in a time-specific manner.PGC-1α-mediated branched-chain amino acid metabolism in the skeletal muscle.Overexpression of PGC-1α increases fatty acid oxidative capacity of human skeletal muscle cells.Neuroendocrine and metabolic components of dopamine agonist amelioration of metabolic syndrome in SHR rats Differential effects of krill oil and fish oil on the hepatic transcriptome in mice Metabolomic Analysis of the Skeletal Muscle of Mice Overexpressing PGC-1α The role of mitochondria in the pathogenesis of type 2 diabetes Improving insulin sensitivity with HDAC inhibitor Probing the relationship between insulin sensitivity and longevity using genetically modified mice PGC-1α overexpression protects against aldosterone-induced podocyte depletion: role of mitochondria.Inactivation of GSK-3beta by metallothionein prevents diabetes-related changes in cardiac energy metabolism, inflammation, nitrosative damage, and remodeling Genetic disruption of SOD1 gene causes glucose intolerance and impairs β-cell function.Genetic models of PGC-1 and glucose metabolism and homeostasis Regulation of skeletal muscle cell plasticity by the peroxisome proliferator-activated receptor γ coactivator 1α.PGC-1 coactivators in cardiac development and disease Dissociating fatty liver and diabetes Functional crosstalk of PGC-1 coactivators and inflammation in skeletal muscle pathophysiology.The Cancer Drug Dasatinib Increases PGC-1α in Adipose Tissue but Has Adverse Effects on Glucose Tolerance in Obese Mice.Transcriptional analysis of intramuscular fatty acid composition in the longissimus thoracis muscle of Iberian × Landrace back-crossed pigs.Role of PGC-1α in Vascular Regulation: Implications for Atherosclerosis.Metformin prevents LYRM1-induced insulin resistance in 3T3-L1 adipocytes via a mitochondrial-dependent mechanism.miR-199-sponge transgenic mice develop physiological cardiac hypertrophy.Sustained NFκB inhibition improves insulin sensitivity but is detrimental to muscle health.Regulation of glycemic control by physical activity: a role for mitochondria?10-Hydroxy-2-decenoic acid, a natural product, improves hyperglycemia and insulin resistance in obese/diabetic KK-Ay mice, but does not prevent obesity.Mulberry anthocyanin extract regulates glucose metabolism by promotion of glycogen synthesis and reduction of gluconeogenesis in human HepG2 cells.

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Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity

http://www.wikidata.org/entity/Q37162234

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 10 February 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Whole body overexpression of P ...... and muscle insulin sensitivity

@en

Whole body overexpression of P ...... nd muscle insulin sensitivity.

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type

label

Whole body overexpression of P ...... and muscle insulin sensitivity

@en

Whole body overexpression of P ...... nd muscle insulin sensitivity.

@nl

prefLabel

Whole body overexpression of P ...... and muscle insulin sensitivity

@en

Whole body overexpression of P ...... nd muscle insulin sensitivity.

@nl

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AJPENDO.90292.2008

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American Journal of Physiology - Endocrinology and Metabolism

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Whole body overexpression of P ...... and muscle insulin sensitivity

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Arlan Richardson

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Bogdan Balas

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Bret H Goodpaster

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Huiyun Liang

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John Dube

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Nicolas Musi

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Puntip Tantiwong

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Robert M O'Doherty

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Walter F Ward

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P2860

Insulin signalling and the regulation of glucose and lipid metabolism

Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism

Complex III releases superoxide to both sides of the inner mitochondrial membrane

PGC-1beta in the regulation of hepatic glucose and energy metabolism

Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

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E945-54

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scholarly article

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10.1152/AJPENDO.90292.2008

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4

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Ralph A DeFronzo

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2009-02-10T00:00:00Z

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19208857

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