Selective regulation of TCR signaling pathways by the CD45 protein tyrosine phosphatase during thymocyte development.

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Zfat-deficiency results in a loss of CD3ζ phosphorylation with dysregulation of ERK and Egr activities leading to impaired positive selection.Comparative quantitative analysis of cluster of differentiation 45 antigen expression on lymphocyte subsets.

P2860

Q35009304-0F9D5268-0C64-4B04-A88D-C8279F209D09 Q35085501-E7E437D4-9D14-4D2D-8D0F-9FB039F10D56

P2860

Selective regulation of TCR signaling pathways by the CD45 protein tyrosine phosphatase during thymocyte development.

Item

http://www.wikidata.org/entity/Q37166168

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2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年学术文章

@wuu

2008年学术文章

@zh-cn

2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

Selective regulation of TCR si ...... during thymocyte development.

@en

Selective regulation of TCR si ...... during thymocyte development.

@nl

type

Item

label

Selective regulation of TCR si ...... during thymocyte development.

@en

Selective regulation of TCR si ...... during thymocyte development.

@nl

prefLabel

Selective regulation of TCR si ...... during thymocyte development.

@en

Selective regulation of TCR si ...... during thymocyte development.

@nl

P1476

Selective regulation of TCR si ...... during thymocyte development.

@en

P2093

David Leitenberg

http://www.w3.org/2001/XMLSchema#string

Rustom Falahati

http://www.w3.org/2001/XMLSchema#string

P2860

Profound block in thymocyte development in mice lacking p56lck

A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells.

Essential role of LAT in T cell development

Staging and resetting T cell activation in SMACs

Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation

Regulation of the p70zap tyrosine protein kinase in T cells by the CD45 phosphotyrosine phosphatase

Expression of the p56(Lck) Y505F mutation in CD45-deficient mice rescues thymocyte development

Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation

Development of T-leukaemias in CD45 tyrosine phosphatase-deficient mutant lck mice

P304

6082-6091

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scholarly article

P356

10.4049/JIMMUNOL.181.9.6082

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P407

English

P433

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P478

181

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P577

2008-11-01T00:00:00Z

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P5875

23403185

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P698

18941197

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P932

2671959

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Selective regulation of TCR signaling pathways by the CD45 protein tyrosine phosphatase during thymocyte development.

about

P2860

P2860

Selective regulation of TCR signaling pathways by the CD45 protein tyrosine phosphatase during thymocyte development.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P932