Defining the molecular mechanisms of human cell immortalization.
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TIN2, a new regulator of telomere length in human cellsNek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblastsCDK4 and CDK6 delay senescence by kinase-dependent and p16INK4a-independent mechanismsAllosteric inhibitors of telomerase: oligonucleotide N3'-->P5' phosphoramidatesA biomarker that identifies senescent human cells in culture and in aging skin in vivoExtension of the replicative life span of human diploid fibroblasts by inhibition of the p33ING1 candidate tumor suppressorCellular Senescence as the Causal Nexus of AgingIdentification of an invasive, N-cadherin-expressing epithelial cell type in endometriosis using a new cell culture modelStra6, a retinoic acid-responsive gene, participates in p53-induced apoptosis after DNA damage.Hepatitis B virus X protein overcomes oncogenic RAS-induced senescence in human immortalized cells.Modeling platinum sensitive and resistant high-grade serous ovarian cancer: development and applications of experimental systems.Phenotypic and in vivo functional characterization of immortalized human fetal liver cells.The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.mTOR Signaling from Cellular Senescence to Organismal AgingSenescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci.Establishment of Hertwig's epithelial root sheath/epithelial rests of Malassez cell line from human periodontium.Enumeration of the simian virus 40 early region elements necessary for human cell transformationhTERT extends the life of human fibroblasts without compromising type I interferon signaling.Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells.Role of telomeres and telomerase in cancerTelomere length modulation in human astroglial brain tumorsInduction of telomere dysfunction mediated by the telomerase substrate precursor 6-thio-2'-deoxyguanosine.An Update on the Biology of RAS/RAF Mutations in Colorectal Cancer.High-mobility group A2 protein modulates hTERT transcription to promote tumorigenesis.Telomerase activity in human ovarian carcinomaUbiquitin-independent proteasomal degradation during oncogenic viral infections.Mammary transplantation of stromal cells and carcinoma cells in C57BL/6J miceSenescence, immortalization, and apoptosis. An intriguing relationship.Telomeres and telomerase in normal and cancer stem cellsCan ends justify the means?: telomeres and the mechanisms of replicative senescence and immortalization in mammalian cellsThe mitotic clock in skeletal muscle regeneration, disease and cell mediated gene therapy.The Asian-American E6 variant protein of human papillomavirus 16 alone is sufficient to promote immortalization, transformation, and migration of primary human foreskin keratinocytes.Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndromeEstablishment of an immortalised human ovarian surface epithelial cell line without chromosomal instability.Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytesRestoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells.Oxidative stress under ambient and physiological oxygen tension in tissue culture.Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization.Nuclear Factor κB1/RelA Mediates Inflammation in Human Lung Epithelial Cells at Atmospheric Oxygen Levels.Role of Telomeres and Telomerase in Aging and Cancer.
P2860
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P2860
Defining the molecular mechanisms of human cell immortalization.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Defining the molecular mechanisms of human cell immortalization.
@en
Defining the molecular mechanisms of human cell immortalization.
@nl
type
label
Defining the molecular mechanisms of human cell immortalization.
@en
Defining the molecular mechanisms of human cell immortalization.
@nl
prefLabel
Defining the molecular mechanisms of human cell immortalization.
@en
Defining the molecular mechanisms of human cell immortalization.
@nl
P2093
P1476
Defining the molecular mechanisms of human cell immortalization.
@en
P2093
P356
10.1016/0304-419X(91)90003-4
P407
P577
1991-04-01T00:00:00Z