Can ends justify the means?: telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells
about
TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpressionMolecular interactions between telomerase and the tumor suppressor protein p53 in vitroA novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancerSp1 and Sp3 recruit histone deacetylase to repress transcription of human telomerase reverse transcriptase (hTERT) promoter in normal human somatic cellsExpression of telomerase subunits in normal and neoplastic prostate epithelial cells isolated by laser capture microdissection.Genome-wide differential gene expression in immortalized DF-1 chicken embryo fibroblast cell lineCharacteristics of primary and immortalized fibroblast cells derived from the miniature and domestic pigs.Hepatitis B virus X protein overcomes oncogenic RAS-induced senescence in human immortalized cells.Distinct mechanisms of cell cycle arrest control the decision between differentiation and senescence in human neuroblastoma cells.Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor.Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristicsN-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo.Enumeration of the simian virus 40 early region elements necessary for human cell transformationTelomerase activation, cellular immortalization and cancer.Human arteries engineered in vitro.C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activity.Biallelic mutations in p16(INK4a) confer resistance to Ras- and Ets-induced senescence in human diploid fibroblastsRoles of homocysteine in cell metabolism: old and new functions.Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cellsDecrease in telomerase activity in U-87MG human glioblastomas after treatment with an antagonist of growth hormone-releasing hormone.A novel strategy for targeted killing of tumor cells: Induction of multipolar acentrosomal mitotic spindles with a quinazolinone derivative mdivi-1.Human papillomavirus E7 repression in cervical carcinoma cells initiates a transcriptional cascade driven by the retinoblastoma family, resulting in senescence.Assessment of Telomere Length in Archived Formalin-Fixed, Paraffinized Human Tissue Is Confounded by Chronological Age and Storage Duration.Effects of estrogen on growth plate senescence and epiphyseal fusion.Constitutive and regulated expression of telomerase reverse transcriptase (hTERT) in human lymphocytesTelomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood.hTR repressor-related gene on human chromosome 10p15.1.Distinct tumor suppressor mechanisms evolve in rodent species that differ in size and lifespan.Repression of the human papillomavirus E6 gene initiates p53-dependent, telomerase-independent senescence and apoptosis in HeLa cervical carcinoma cells.Telomere organization in the ligninolytic basidiomycete Pleurotus ostreatusRapid induction of senescence in human cervical carcinoma cells.Repression of the SUMO-specific protease Senp1 induces p53-dependent premature senescence in normal human fibroblasts.One-step immortalization of primary human airway epithelial cells capable of oncogenic transformation.Enhancing the efficacy of mesenchymal stem cell therapy.Conditional immortalization of primary adipocyte precursor cells.Putative telomere-recruiting domain in the catalytic subunit of human telomerase.Spontaneously immortalized mouse mesothelial cells display characteristics of malignant transformation.Human pulp-derived cells immortalized with Simian Virus 40 T-antigen.Modulation of p53 expression and its role in the conversion to a fully immortalized chicken embryo fibroblast line.Immortalization and transformation of primary human airway epithelial cells by gene transfer.
P2860
Q24291448-9B66D953-419D-4584-924D-4FBA0A1D75ADQ28118564-D1148886-4B51-44DF-BFFF-F7FE9E464298Q28210555-BA7121C5-65A5-4CF4-82F2-5177331A71D0Q28216580-0F0F3883-D053-4E2D-B691-F7221A9DF241Q30779078-2DDE63F9-6125-4CF1-919A-2FD27BBF3C33Q31042174-6E789E7E-26B9-4427-839A-AD5B2DB4234EQ33286432-F4439D69-3CD1-4033-A886-FE1A3CBE17A9Q33296078-FCC25BEF-5115-4C6F-97ED-33952D18CEC8Q33931217-971BE427-FD97-4082-8444-993B2A3482B5Q33961286-C8E2FAD3-9A34-487B-866F-364A9F27F7A9Q33962085-6165008F-B33C-47B5-BDD1-E788018E648FQ34012762-8327632E-2066-494C-9621-A4827215E496Q34117528-A80216A4-FA97-4075-A402-2A011063548FQ34235187-96875CF9-D634-47DA-B465-AB6775424E6AQ34236694-82379619-CD28-48FA-A3B8-C89065ABC834Q34285674-BD4F40D6-52BB-4DC9-98D0-E6A81CD4DD3AQ34286570-A5A3ECB2-2B5D-495B-A92F-3641C4C22F6DQ34308857-E96B661A-7277-4258-ADDE-286813C6851FQ34465477-42ACCCC7-D7C3-470C-8669-7C2678540AB9Q34801437-ACE306C1-B02C-4B2F-A596-7E4FD5191AF1Q35007986-02DC27A7-AE99-4948-A214-EC3CE22DE81AQ35784727-D9A556A0-7B87-4F20-8F27-090202A30096Q36123831-037C93E6-6FC7-43D0-88A6-D29459DDF9A3Q36240179-B593197D-6DFA-4E86-B30C-4E619C7EBEE6Q36338644-E1D585D4-1B93-406F-9FFA-4A0A2A02648AQ36375132-57B44045-C808-410E-BF8F-C432AD7B036AQ36623170-8C26A7F1-5DD8-47B1-AE77-C292A4477910Q37086921-24B4B9D4-5CC5-49AA-9A5C-BA44E226E64BQ37094001-E29608AA-7AD6-4AAB-BC16-8AEE0F93EFB3Q37110436-109800CB-CEDA-4D22-A6FD-D9D80C85971DQ37268828-D2DCC8FA-1DD6-456E-882C-0442F47016B9Q37349403-88E1C98F-5C6F-429B-900F-F0D8A020B6C1Q37410396-2E62B353-E42F-4BB6-B0F3-75BE1FED355AQ37723500-44ED93B9-B399-447D-BCD3-D09B89E7B14DQ38844951-1574CFF5-FEEB-4CE5-BFE8-EFCDE91CAB2DQ39745847-349E05E4-3655-42D4-9E8A-F86DE2613378Q39911135-A71DE487-6A0D-4F57-AD77-218666BE1F77Q40289280-5735AAD4-C215-4CB7-A7C6-EE05400B81B6Q40346718-DD38FA84-DF04-473F-A61B-686F56BD2740Q40722115-D41E033C-43C8-4C2E-B306-294A356E5EEB
P2860
Can ends justify the means?: telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Can ends justify the means?: t ...... rtalization in mammalian cells
@ast
Can ends justify the means?: t ...... rtalization in mammalian cells
@en
type
label
Can ends justify the means?: t ...... rtalization in mammalian cells
@ast
Can ends justify the means?: t ...... rtalization in mammalian cells
@en
prefLabel
Can ends justify the means?: t ...... rtalization in mammalian cells
@ast
Can ends justify the means?: t ...... rtalization in mammalian cells
@en
P2860
P356
P1476
Can ends justify the means?: t ...... rtalization in mammalian cells
@en
P2093
J M Sedivy
P2860
P304
P356
10.1073/PNAS.95.16.9078
P407
P577
1998-08-01T00:00:00Z