Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension.
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Adenoviral expression of a transforming growth factor-beta1 antisense mRNA is effective in preventing liver fibrosis in bile-duct ligated ratsComparative evaluation of gene delivery devices in primary cultures of rat hepatic stellate cells and rat myofibroblastsEfficient hepatic delivery of drugs: novel strategies and their significancePhosphodiesterase-5 inhibitors have distinct effects on the hemodynamics of the liverChronic intermittent hypoxia induces NMDA receptor-dependent plasticity and suppresses nitric oxide signaling in the mouse hypothalamic paraventricular nucleus.A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension.The paradox of nitric oxide in cirrhosis and portal hypertension: too much, not enough.Hepatic stellate cells: role in microcirculation and pathophysiology of portal hypertension.Integrin-linked kinase regulates endothelial cell nitric oxide synthase expression in hepatic sinusoidal endothelial cells.Vascular pathobiology in chronic liver disease and cirrhosis - current status and future directions.Research progress of vasculopathy in portal hypertension.G protein-coupled receptor kinases: more than just kinases and not only for GPCRsTargeted treatments for cirrhosis.Divergent transforming growth factor-beta signaling in hepatic stellate cells after liver injury: functional effects on ECE-1 regulationNCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertensionStellate cell contraction: role, regulation, and potential therapeutic target.Targeted RNA interference for hepatic fibrosis.Addition of simvastatin to carvedilol non responders: A new pharmacological therapy for treatment of portal hypertension.Endothelial dysfunction in the regulation of cirrhosis and portal hypertension.Current concepts on the role of nitric oxide in portal hypertension.Pathophysiology of portal hypertension and its clinical links.Evolution in the understanding of the pathophysiological basis of portal hypertension: How changes in paradigm are leading to successful new treatments.The Molecular Basis of Portal Hypertension.In vivo gene transfer of endothelial nitric oxide synthase decreases portal pressure in anaesthetised carbon tetrachloride cirrhotic rats.Hemodynamic and antifibrotic effects of a selective liver nitric oxide donor V-PYRRO/NO in bile duct ligated rats.Influence of caveolin on constitutively activated recombinant eNOS: insights into eNOS dysfunction in BDL rat liver.Fibronectin stimulates endothelin-1 synthesis in rat hepatic myofibroblasts via a Src/ERK-regulated signaling pathway.Intrahepatic upregulation of RhoA and Rho-kinase signalling contributes to increased hepatic vascular resistance in rats with secondary biliary cirrhosis.Synaptic and vascular associations of neurons containing cyclooxygenase-2 and nitric oxide synthase in rat somatosensory cortex.Role of endothelial nitric oxide synthase in the development of portal hypertension in the carbon tetrachloride-induced liver fibrosis model.Obstructive jaundice activates nitroxidergic neurons of the vago-vagal neural circuit that regulates the hepatobiliary system in rabbits.Effect of chronic ethanol administration on hepatic eNOS activity and its association with caveolin-1 and calmodulin in female rats.Intrahepatic vascular changes in non-alcoholic fatty liver disease: Potential role of insulin-resistance and endothelial dysfunction.Dominant-negative soluble PDGF-beta receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis.Brain nitric oxide synthase expression is enhanced in the human cervix in labor.Evaluation of portal pressure by doppler ultrasound in patients with cirrhosis before and after simvastatin administration - a randomized controlled trial.Analysis of the nitric oxide-cyclic guanosine monophosphate pathway in experimental liver cirrhosis suggests phosphodiesterase-5 as potential target to treat portal hypertension
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Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2000
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Gene transfer of the neuronal ...... eliorates portal hypertension.
@en
Gene transfer of the neuronal ...... eliorates portal hypertension.
@nl
type
label
Gene transfer of the neuronal ...... eliorates portal hypertension.
@en
Gene transfer of the neuronal ...... eliorates portal hypertension.
@nl
prefLabel
Gene transfer of the neuronal ...... eliorates portal hypertension.
@en
Gene transfer of the neuronal ...... eliorates portal hypertension.
@nl
P2093
P2860
P356
P1476
Gene transfer of the neuronal ...... eliorates portal hypertension.
@en
P2093
P2860
P304
P356
10.1172/JCI7997
P407
P577
2000-03-01T00:00:00Z