Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats - Wikidata - awgldk - TriplyDB

Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats

Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats

http://www.wikidata.org/entity/Q37176157

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Blockade of islet amyloid polypeptide fibrillation and cytotoxicity by the secretory chaperones 7B2 and proSAAS Neuroendocrine secretory protein 7B2: structure, expression and functions Regulation of the hypothalamic thyrotropin releasing hormone (TRH) neuron by neuronal and peripheral inputs Mechanisms of action of glucagon-like peptide 1 in the pancreas Is GLP-1 a hormone: Whether and When?Carbohydrate-induced secretion of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 GLP-1-based strategies: a physiological analysis of differential mode of action Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease Regulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoter Incretin receptor null mice reveal key role of GLP-1 but not GIP in pancreatic beta cell adaptation to pregnancy.Role of endogenous GLP-1 and GIP in beta cell compensatory responses to insulin resistance and cellular stress.Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic α-cells in mouse models of ß-cell regeneration.Glucagon-like peptide-1 synthetic analogs: new therapeutic agents for use in the treatment of diabetes mellitus.Hepatic and glucagon-like peptide-1-mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors.Knockdown of Pdcd4 results in induction of proprotein convertase 1/3 and potent secretion of chromogranin A and secretogranin II in a neuroendocrine cell line.Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells.Improving function and survival of pancreatic islets by endogenous production of glucagon-like peptide 1 (GLP-1).Activation of the GLP-1 receptor signalling pathway: a relevant strategy to repair a deficient beta-cell mass Chronic exposure to GLP-1 increases GLP-1 synthesis and release in a pancreatic alpha cell line (α-TC1): evidence of a direct effect of GLP-1 on pancreatic alpha cells Glucagon is essential for alpha cell transdifferentiation and beta cell neogenesis.Nutrient induced type 2 and chemical induced type 1 experimental diabetes differently modulate gastric GLP-1 receptor expression.Glucagon-like peptide 1: evolution of an incretin into a treatment for diabetes.Endogenous GLP-1 as a key self-defense molecule against lipotoxicity in pancreatic islets Heterogeneity of glucagonomas due to differential processing of proglucagon-derived peptides.Activation of Transmembrane Bile Acid Receptor TGR5 Modulates Pancreatic Islet α Cells to Promote Glucose Homeostasis.Global gene expression profiling of pancreatic islets in mice during streptozotocin-induced β-cell damage and pancreatic Glp-1 gene therapy.Morphine treatment selectively regulates expression of rat pituitary POMC and the prohormone convertases PC1/3 and PC2.Growth factor control of pancreatic islet regeneration and function Treatment of diabetes with glucagon-like peptide-1 gene therapy.Reprogramming gut and pancreas endocrine cells to treat diabetes.α-cell role in β-cell generation and regeneration.GLP-1 effects on islets: hormonal, neuronal, or paracrine?Islet α cells and glucagon--critical regulators of energy homeostasis.Evolving function and potential of pancreatic alpha cells.Intra-islet glucagon-like peptide 1.The New Biology and Pharmacology of Glucagon.Do we know the true mechanism of action of the DPP-4 inhibitors?Stromal cell-derived factor-1 (SDF-1)/chemokine (C-X-C motif) receptor 4 (CXCR4) axis activation induces intra-islet glucagon-like peptide-1 (GLP-1) production and enhances beta cell survival Altered proglucagon processing in an alpha-cell line derived from prohormone convertase 2 null mouse islets.The role of β cell glucagon-like peptide-1 signaling in glucose regulation and response to diabetes drugs.

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Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats

http://www.wikidata.org/entity/Q37176157

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scientific article published on April 2000

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Regulation of pancreatic PC1 a ...... ike peptide 1 in diabetic rats

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Regulation of pancreatic PC1 a ...... ke peptide 1 in diabetic rats.

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Regulation of pancreatic PC1 a ...... ike peptide 1 in diabetic rats

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Regulation of pancreatic PC1 a ...... ke peptide 1 in diabetic rats.

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Regulation of pancreatic PC1 a ...... ike peptide 1 in diabetic rats

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Regulation of pancreatic PC1 a ...... ke peptide 1 in diabetic rats.

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Journal of Clinical Investigation

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Regulation of pancreatic PC1 a ...... ike peptide 1 in diabetic rats

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D Pipeleers

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E Jansen

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M Nakashima

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Q L Li

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T C Friedman

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Y Nie

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P2860

Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum

GLUT2 in pancreatic islets: crucial target molecule in diabetes induced with multiple low doses of streptozotocin in mice

Brief report: impaired processing of prohormones associated with abnormalities of glucose homeostasis and adrenal function

Neuroendocrine-specific expression of the human prohormone convertase 1 gene. Hormonal regulation of transcription through distinct cAMP response elements

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats

Regulation of prohormone convertase 1 (PC1) by gp130-related cytokines

Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3

The proprotein convertases

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10.1172/JCI7456

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