Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis - Wikidata - awgldk - TriplyDB

Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis

Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis

http://www.wikidata.org/entity/Q37188579

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Mitochondria-associated membranes as hubs for neurodegeneration Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome A point mutation in the [2Fe–2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties A neurodegenerative perspective on mitochondrial optic neuropathies MitoNEET Protects HL-1 Cardiomyocytes from Oxidative Stress Mediated Apoptosis in an In Vitro Model of Hypoxia and Reoxygenation A novel CISD2 mutation associated with a classical Wolfram syndrome phenotype alters Ca2+ homeostasis and ER-mitochondria interactions.ER-mitochondrial calcium flow underlies vulnerability of mechanosensory hair cells to damage.A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome The Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer.Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function.Dysregulation of Mitochondrial Functions and Osteogenic Differentiation in Cisd2-Deficient Murine Induced Pluripotent Stem Cells Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth.Redox control of human mitochondrial outer membrane protein MitoNEET [2Fe-2S] clusters by biological thiols and hydrogen peroxide.Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1.Iron: the hard player in diabetes pathophysiology.Cisd2 mediates lifespan: is there an interconnection among Ca²⁺ homeostasis, autophagy, and lifespan?Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis.A novel link between Fic (filamentation induced by cAMP)-mediated adenylylation/AMPylation and the unfolded protein response Reduction of mitochondrial protein mitoNEET [2Fe-2S] clusters by human glutathione reductase.MitoNEET (CISD1) Knockout Mice Show Signs of Striatal Mitochondrial Dysfunction and a Parkinson's Disease Phenotype.In situ measurements of mitochondrial matrix enzyme activities using plasma and mitochondrial membrane permeabilization agents.Comparative proteomic profiling reveals a role for Cisd2 in skeletal muscle aging.The unique fold and lability of the [2Fe-2S] clusters of NEET proteins mediate their key functions in health and disease.Clinical Characteristics of Wolfram Syndrome in Chinese Population and a Novel Frameshift Mutation in WFS1.Phylogenetic analysis of the CDGSH iron-sulfur binding domain reveals its ancient origin.Wolfram syndrome: MAMs' connection?

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Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis

http://www.wikidata.org/entity/Q37188579

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 24 May 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Wolfram Syndrome protein, Mine ...... response, and Ca2+ homeostasis

@en

Wolfram Syndrome protein, Mine ...... esponse, and Ca2+ homeostasis.

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type

label

Wolfram Syndrome protein, Mine ...... response, and Ca2+ homeostasis

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Wolfram Syndrome protein, Mine ...... esponse, and Ca2+ homeostasis.

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Wolfram Syndrome protein, Mine ...... response, and Ca2+ homeostasis

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Wolfram Syndrome protein, Mine ...... esponse, and Ca2+ homeostasis.

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EMBO Molecular Medicine

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Wolfram Syndrome protein, Mine ...... response, and Ca2+ homeostasis

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Ajit S Divakaruni

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Alexander Y Andreyev

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Benjamin G Neel

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Estelle A Wall

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Guy Perkins

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Jack E Dixon

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Melvin I Simon

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Peter van der Geer

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Robert Karisch

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Sandra E Wiley

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P2860

Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) caused by mutations in a novel gene (wolframin) coding for a predicted transmembrane protein

Wolframin expression induces novel ion channel activity in endoplasmic reticulum membranes and increases intracellular calcium

Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

WFS1 protein modulates the free Ca(2+) concentration in the endoplasmic reticulum

Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2

Role of SERCA1 truncated isoform in the proapoptotic calcium transfer from ER to mitochondria during ER stress

Making heads or tails of phospholipids in mitochondria

MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone

High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria

MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity

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904-918

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scholarly article

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10.1002/EMMM.201201429

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6

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2013-05-24T00:00:00Z

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3779451

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