Merotelic kinetochore orientation, aneuploidy, and cancer.
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Nuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitorChromosomal instability and cancer: a complex relationship with therapeutic potentialRegulation of kinetochore-microtubule attachments through homeostatic control during mitosisAurora B hyperactivation by Bub1 overexpression promotes chromosome missegregationBasic mechanism for biorientation of mitotic chromosomes is provided by the kinetochore geometry and indiscriminate turnover of kinetochore microtubules.Live imaging RNAi screen reveals genes essential for meiosis in mammalian oocytes.Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entryIntratumour diversity of chromosome copy numbers in neuroblastoma mediated by on-going chromosome loss from a polyploid stateMultipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cellsTranscriptional control of mitosis: deregulation and cancerA mechanism linking extra centrosomes to chromosomal instabilityTemporal changes in Hec1 phosphorylation control kinetochore-microtubule attachment stability during mitosis.Dynamic bonds and polar ejection force distribution explain kinetochore oscillations in PtK1 cells.Chk2 prevents mitotic exit when the majority of kinetochores are unattached.Spatial regulation of astral microtubule dynamics by Kif18B in PtK cells.RNAi mediated acute depletion of retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation.Overexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation.Laser microsurgery provides evidence for merotelic kinetochore attachments in fission yeast cells lacking Pcs1 or Clr4.Mechanisms and consequences of aneuploidy and chromosome instability in the aging brainFunctional interactions between retinoblastoma and c-MYC in a mouse model of hepatocellular carcinoma.Vertebrate kinetochore protein architecture: protein copy number.Causes and consequences of centrosome abnormalities in cancer.Centriole duplication: A lesson in self-control.CKAP2 ensures chromosomal stability by maintaining the integrity of microtubule nucleation sites.Stochastic approach to the molecular counting problem in superresolution microscopyBub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivationTumor-specific chromosome mis-segregation controls cancer plasticity by maintaining tumor heterogeneityMultimodal effects of small molecule ROCK and LIMK inhibitors on mitosis, and their implication as anti-leukemia agents.Illicit survival of cancer cells during polyploidization and depolyploidization.Chromosomal instability as a prognostic marker in cervical cancer.Chromosomal instability substantiates poor prognosis in patients with diffuse large B-cell lymphoma.Timing of centrosome separation is important for accurate chromosome segregation.Targeting karyotypic complexity and chromosomal instability of cancer cells.Doubling the deck: Tetraploidy induces chromosome shuffling and cancerLinking abnormal mitosis to the acquisition of DNA damageTurning the headlights on novel cancer biomarkers: Inspection of mechanics underlying intratumor heterogeneitySelective advantage of trisomic human cells cultured in non-standard conditionsNonrandom distribution of interhomolog recombination events induced by breakage of a dicentric chromosome in Saccharomyces cerevisiae.The composition, functions, and regulation of the budding yeast kinetochoreMulti-layered cancer chromosomal instability phenotype.
P2860
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P2860
Merotelic kinetochore orientation, aneuploidy, and cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 May 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Merotelic kinetochore orientation, aneuploidy, and cancer.
@en
Merotelic kinetochore orientation, aneuploidy, and cancer.
@nl
type
label
Merotelic kinetochore orientation, aneuploidy, and cancer.
@en
Merotelic kinetochore orientation, aneuploidy, and cancer.
@nl
prefLabel
Merotelic kinetochore orientation, aneuploidy, and cancer.
@en
Merotelic kinetochore orientation, aneuploidy, and cancer.
@nl
P1476
Merotelic kinetochore orientation, aneuploidy, and cancer
@en
P2093
Daniela Cimini
P356
10.1016/J.BBCAN.2008.05.003
P407
P577
2008-05-23T00:00:00Z