Inhibition and induction of human cytochrome P450 enzymes: current status. - Wikidata - awgldk - TriplyDB

Inhibition and induction of human cytochrome P450 enzymes: current status.

Inhibition and induction of human cytochrome P450 enzymes: current status.

http://www.wikidata.org/entity/Q37212794

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Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease Pharmacokinetic drug interactions in liver disease: An update Pharmacokinetic interactions of herbs with cytochrome p450 and p-glycoprotein Predicting drug-target interaction networks based on functional groups and biological features A unified proteochemometric model for prediction of inhibition of cytochrome p450 isoforms Up-regulating CYP3A4 expression in C3A cells by transfection with a novel chimeric regulator of hPXR-p53-AD Computational prediction of metabolism: sites, products, SAR, P450 enzyme dynamics, and mechanisms Cardiac safety of ophthalmic timolol.Drug-botanical interactions: a review of the laboratory, animal, and human data for 8 common botanicals.Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity.Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator Effects of nicotine on cytochrome P450 2A6 and 2E1 activities.Epidemiology of idiosyncratic drug-induced liver injury Preliminary investigation of the contribution of CYP2A6, CYP2B6, and UGT1A9 polymorphisms on artesunate-mefloquine treatment response in Burmese patients with Plasmodium falciparum malaria.Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.Evaluation of metabolism-mediated herb-drug interactions.Cytochrome P450 induction properties of food and herbal-derived compounds using a novel multiplex RT-qPCR in vitro assay, a drug-food interaction prediction tool Prediction of Cytochrome P450 Profiles of Environmental Chemicals with QSAR Models Built from Drug-like Molecules.Sucralose, a synthetic organochlorine sweetener: overview of biological issues Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implications Effects of eleutheroside B and eleutheroside E on activity of cytochrome P450 in rat liver microsomes.In silico toxicology - non-testing methods.Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver.Development and validation of a reversed-phase HPLC method for CYP1A2 phenotyping by use of a caffeine metabolite ratio in saliva.Clinically relevant drug-drug interactions between antiretrovirals and antifungals Effects of brown rice and white rice on expression of xenobiotic metabolism genes in type 2 diabetic rats.A population-based analysis of the risk of drug interaction between clarithromycin and statins for hospitalisation or death.Development of NanoART for HIV Treatment: Minding the Cytochrome P450 (CYP) Enzymes Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevance Molecular mechanisms underlying chemical liver injury.Effects of ospemifene on drug metabolism mediated by cytochrome P450 enzymes in humans in vitro and in vivo.Antiretroviral drug interactions: overview of interactions involving new and investigational agents and the role of therapeutic drug monitoring for management.Effects of pharmaceuticals and other active chemicals at biological targets: mechanisms, interactions, and integration into PB-PK/PD models.The effect of piperine on midazolam plasma concentration in healthy volunteers, a research on the CYP3A-involving metabolism.Species differences in the hepatic effects of inducers of CYP2B and CYP4A subfamily forms: relationship to rodent liver tumour formation.QSAR of cytochrome inhibitors.Cytochrome P450 and P-Glycoprotein-Mediated Interactions Involving African Herbs Indicated for Common Noncommunicable Diseases.Drug interactions with antiretrovirals and warfarin.Ambient tonicity and intestinal cytochrome CYP3A.Sources of variability in ketoconazole inhibition of human cytochrome P450 3A in vitro.

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P2860

Inhibition and induction of human cytochrome P450 enzymes: current status.

http://www.wikidata.org/entity/Q37212794

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 11 July 2008

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Inhibition and induction of human cytochrome P450 enzymes: current status.

@en

Inhibition and induction of human cytochrome P450 enzymes: current status.

@nl

type

label

Inhibition and induction of human cytochrome P450 enzymes: current status.

@en

Inhibition and induction of human cytochrome P450 enzymes: current status.

@nl

prefLabel

Inhibition and induction of human cytochrome P450 enzymes: current status.

@en

Inhibition and induction of human cytochrome P450 enzymes: current status.

@nl

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Archives of Toxicology

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Inhibition and induction of human cytochrome P450 enzymes: current status.

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Hannu Raunio

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Janne Hukkanen

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Jukka Hakkola

http://www.w3.org/2001/XMLSchema#string

Miia Turpeinen

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Olavi Pelkonen

http://www.w3.org/2001/XMLSchema#string

Paavo Honkakoski

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P2860

The effects of selective serotonin reuptake inhibitors and their metabolites on S-mephenytoin 4'-hydroxylase activity in human liver microsomes

Human liver microsomal metabolism of paclitaxel and drug interactions

DNA adduct formation from tobacco-specific N-nitrosamines.

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene.

Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism

Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms.

In vitro proguanil activation to cycloguanil by human liver microsomes is mediated by CYP3A isoforms as well as by S-mephenytoin hydroxylase.

CYP3A4 and CYP2A6 activities marked by the metabolism of lignocaine and coumarin in patients with liver and kidney diseases and epileptic patients.

Comparative effects of the antimycotic drugs ketoconazole, fluconazole, itraconazole and terbinafine on the metabolism of cyclosporin by human liver microsomes

Accumulation of caffeine in healthy volunteers treated with furafylline

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s00204-008-0332-8

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667-715

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10.1007/S00204-008-0332-8

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10

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82

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2008-07-11T00:00:00Z

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5234753

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18618097

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