Species differences in the hepatic effects of inducers of CYP2B and CYP4A subfamily forms: relationship to rodent liver tumour formation.
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Critical role of toxicologic pathology in a short-term screen for carcinogenicityMode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activatorPhenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of actionEffects of the PPARα Agonist and Widely Used Antihyperlipidemic Drug Gemfibrozil on Hepatic Toxicity and Lipid Metabolism.Small-molecule modulators of the constitutive androstane receptor.Small-molecule modulators of PXR and CAR.Liver hypertrophy: a review of adaptive (adverse and non-adverse) changes--conclusions from the 3rd International ESTP Expert Workshop.Xenobiotic receptor humanized mice and their utility.Human relevance framework for rodent liver tumors induced by the insecticide sulfoxaflor.Mode of action analysis for pesticide-induced rodent liver tumours involving activation of the constitutive androstane receptor: relevance to human cancer risk.Human and primate-specific microRNAs in cancer: Evolution, and significance in comparison with more distantly-related research models: The great potential of evolutionary young microRNA in cancer research.Mode of action analysis for rat hepatocellular tumors produced by the synthetic pyrethroid momfluorothrin: evidence for activation of the constitutive androstane receptor (CAR) and mitogenicity in rat hepatocytes.Hepatic microRNA profiles offer predictive and mechanistic insights after exposure to genotoxic and epigenetic hepatocarcinogens.Primate-specific Long Non-coding RNAs and MicroRNAs.Human hepatocytes support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogen sodium phenobarbital in an in vivo study using a chimeric mouse with humanized liver.Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo.Integration of novel approaches demonstrates simultaneous metabolic inactivation and CAR-mediated hepatocarcinogenesis of a nitrification inhibitor.Sedaxane-Use of Nuclear Receptor Transactivation Assays, Toxicogenomics, and Toxicokinetics as Part of a Mode of Action Framework for Rodent Liver Tumors.Stem Cell-Based Toxicity ScreeningHuman relevance of rodent liver tumour formation by constitutive androstane receptor (CAR) activators
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P2860
Species differences in the hepatic effects of inducers of CYP2B and CYP4A subfamily forms: relationship to rodent liver tumour formation.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Species differences in the hep ...... rodent liver tumour formation.
@en
Species differences in the hep ...... rodent liver tumour formation.
@nl
type
label
Species differences in the hep ...... rodent liver tumour formation.
@en
Species differences in the hep ...... rodent liver tumour formation.
@nl
prefLabel
Species differences in the hep ...... rodent liver tumour formation.
@en
Species differences in the hep ...... rodent liver tumour formation.
@nl
P2860
P1433
P1476
Species differences in the hep ...... rodent liver tumour formation.
@en
P2093
P2860
P304
P356
10.1080/00498250903098184
P407
P577
2009-08-01T00:00:00Z