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Targeting UDP-galactopyranose mutases from eukaryotic human pathogensCrystal Structures of Trypanosoma cruzi UDP-Galactopyranose Mutase Implicate Flexibility of the Histidine Loop in Enzyme ActivationGolgi-located NTPDase1 of Leishmania major is required for lipophosphoglycan elongation and normal lesion development whereas secreted NTPDase2 is dispensable for virulenceDegradation of host sphingomyelin is essential for Leishmania virulence.Eukaryotic UDP-galactopyranose mutase (GLF gene) in microbial and metazoal pathogens.Stage-specific differential gene expression in Leishmania infantum: from the foregut of Phlebotomus perniciosus to the human phagocyte.Episomally driven antisense mRNA abrogates the hyperinducible expression and function of a unique cell surface class I nuclease in the primitive trypanosomatid parasite, Crithidia luciliae.Leishmania parasites possess a platelet-activating factor acetylhydrolase important for virulence.Plasmenylethanolamine synthesis in Leishmania major.Leishmania salvage and remodelling of host sphingolipids in amastigote survival and acidocalcisome biogenesis.Sphingosine kinase A is a pleiotropic and essential enzyme for Leishmania survival and virulence.Construction of Two mCherry Plasmids (pXG-mCherry) for Transgenic Leishmania: Valuable Tools for Future Molecular Analysis.Galactofuranose in eukaryotes: aspects of biosynthesis and functional impact.Innate immune activation and subversion of Mammalian functions by leishmania lipophosphoglycan.Expression and initial characterization of WbbI, a putative D-Galf:alpha-D-Glc beta-1,6-galactofuranosyltransferase from Escherichia coli K-12.Leishmania cell wall as a potent target for antiparasitic drugs. A focus on the glycoconjugates.Interplay between a cytosolic and a cell surface carbonic anhydrase in pH homeostasis and acid tolerance of Leishmania.Improved orthologous databases to ease protozoan targets inference.A single UDP-galactofuranose transporter is required for galactofuranosylation in Aspergillus fumigatus.Molecular cloning of the Leishmania major UDP-glucose pyrophosphorylase, functional characterization, and ligand binding analyses using NMR spectroscopy.Biosynthesis of galactofuranose in kinetoplastids: novel therapeutic targets for treating leishmaniasis and chagas' disease.Identification and partial characterization of two eukaryotic UDP-galactopyranose mutases.Identification of novel inhibitors against UDP-galactopyranose mutase to combat leishmaniasis.Leishmania infantum Lipophosphoglycan-Deficient Mutants: A Tool to Study Host Cell-Parasite Interplay.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The LPG1 gene family of Leishmania major.
@en
The LPG1 gene family of Leishmania major.
@nl
type
label
The LPG1 gene family of Leishmania major.
@en
The LPG1 gene family of Leishmania major.
@nl
prefLabel
The LPG1 gene family of Leishmania major.
@en
The LPG1 gene family of Leishmania major.
@nl
P2093
P2860
P1476
The LPG1 gene family of Leishmania major.
@en
P2093
Salvatore J Turco
Tamara Barron
P2860
P356
10.1016/J.MOLBIOPARA.2004.02.012
P577
2004-07-01T00:00:00Z