Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition
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Hsp90 inhibitors exhibit resistance-free antiviral activity against respiratory syncytial virusDifferential heat shock protein localization in chronic lymphocytic leukemiaQuantitative proteomics reveals that Hsp90 inhibition preferentially targets kinases and the DNA damage response.Geldanamycin selectively targets the nascent form of ERBB3 for degradationInitial testing (Stage 1) of AT13387, an HSP90 inhibitor, by the pediatric preclinical testing program.Hsp90 molecular chaperone inhibitors: are we there yet?Hsp90 as a therapeutic target in patients with oesophageal carcinoma.Monitoring the induction of heat shock factor 1/heat shock protein 70 expression following 17-allylamino-demethoxygeldanamycin treatment by positron emission tomography and optical reporter gene imaging.Cdc37-Hsp90 complexes are responsive to nucleotide-induced conformational changes and binding of further cofactors.A comparison of cell survival and heat shock protein expression after radiation in normal dermal fibroblasts, microvascular endothelial cells, and different head and neck squamous carcinoma cell lines.The HSP90 chaperone machinery.Antihormone induced compensatory signalling in breast cancer: an adverse event in the development of endocrine resistance.
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Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 30 September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition
@en
Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition.
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type
label
Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition
@en
Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition.
@nl
prefLabel
Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition
@en
Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition.
@nl
P2093
P2860
P356
P1433
P1476
Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition
@en
P2093
Itai Pashtan
Len Neckers
Shinji Tsutsumi
Suiquan Wang
Wanping Xu
P2860
P304
P356
10.4161/CC.7.18.6701
P577
2008-09-30T00:00:00Z