Fibrillar amyloid-beta peptides activate microglia via TLR2: implications for Alzheimer's disease.
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Role of pro-inflammatory cytokines released from microglia in Alzheimer's diseaseApolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's diseaseInnate immunity in Alzheimer's disease: a complex affairM1 and M2 immune activation in Parkinson's Disease: Foe and ally?IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline.Ceramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ AccumulationAlzheimer's associated β-amyloid protein inhibits influenza A virus and modulates viral interactions with phagocytes.Implications of protein structure instability: from physiological to pathological secondary structure.A novel mouse model of Niemann-Pick type C disease carrying a D1005G-Npc1 mutation comparable to commonly observed human mutations.Inflammation, microglia, and Alzheimer's disease.CD36 and TLR interactions in inflammation and phagocytosis: implications for malaria.A Decade of Research on TLR2 Discovering Its Pivotal Role in Glial Activation and Neuroinflammation in Neurodegenerative Diseases.Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's diseaseNeuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microgliaRcor2 underexpression in senescent mice: a target for inflammaging?Amyloid-β(1-42) protofibrils stimulate a quantum of secreted IL-1β despite significant intracellular IL-1β accumulation in microglia.Low-level laser therapy regulates microglial function through Src-mediated signaling pathways: implications for neurodegenerative diseasesMyD88 is dispensable for cerebral amyloidosis and neuroinflammation in APP/PS1 transgenic mice.Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson's disease patients.Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer's disease.Toll-like receptors in Alzheimer's diseaseThe role of the anaphylatoxins in health and disease.Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia.Toll-like receptor 2 -196 to -174 del polymorphism influences the susceptibility of Han Chinese people to Alzheimer's diseaseA single nucleotide polymorphism in primary-microRNA-146a reduces the expression of mature microRNA-146a in patients with Alzheimer's disease and is associated with the pathogenesis of Alzheimer's disease.The biphasic role of microglia in Alzheimer's disease.Gemfibrozil, a lipid-lowering drug, induces suppressor of cytokine signaling 3 in glial cells: implications for neurodegenerative disordersThe critical role of toll-like receptors--From microbial recognition to autoimmunity: A comprehensive review.The changing phenotype of microglia from homeostasis to diseaseNeuroprotective effects of bee venom phospholipase A2 in the 3xTg AD mouse model of Alzheimer's disease.Epithelial cells augment barrier function via activation of the Toll-like receptor 2/phosphatidylinositol 3-kinase pathway upon recognition of Salmonella enterica serovar Typhimurium curli fibrils in the gut.Cocaine-mediated induction of microglial activation involves the ER stress-TLR2 axisAlzheimer disease periventricular white matter lesions exhibit specific proteomic profile alterationsAcute phase proteins are major clients for the chaperone action of α₂-macroglobulin in human plasmaMicroglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein.Microglia dynamics and function in the CNS.Toll-like receptors in atherosclerosisResponses to amyloids of microbial and host origin are mediated through toll-like receptor 2.Neutralization of granulocyte macrophage colony-stimulating factor decreases amyloid beta 1-42 and suppresses microglial activity in a transgenic mouse model of Alzheimer's disease.Neuroinflammation and copper in Alzheimer's disease.
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P2860
Fibrillar amyloid-beta peptides activate microglia via TLR2: implications for Alzheimer's disease.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Fibrillar amyloid-beta peptide ...... tions for Alzheimer's disease.
@en
Fibrillar amyloid-beta peptide ...... tions for Alzheimer's disease.
@nl
type
label
Fibrillar amyloid-beta peptide ...... tions for Alzheimer's disease.
@en
Fibrillar amyloid-beta peptide ...... tions for Alzheimer's disease.
@nl
prefLabel
Fibrillar amyloid-beta peptide ...... tions for Alzheimer's disease.
@en
Fibrillar amyloid-beta peptide ...... tions for Alzheimer's disease.
@nl
P2093
P2860
P921
P1476
Fibrillar amyloid-beta peptide ...... tions for Alzheimer's disease.
@en
P2093
Carlos A Palencia
Kalipada Pahan
Malabendu Jana
P2860
P304
P356
10.4049/JIMMUNOL.181.10.7254
P407
P577
2008-11-01T00:00:00Z