Activity of SQ641, a capuramycin analog, in a murine model of tuberculosis
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New agents for the treatment of drug-resistant Mycobacterium tuberculosisStructural insights into inhibition of lipid I production in bacterial cell wall synthesis.[Better search strategies, hopeful candidates. The search for new antimycobacterial drugs].The cell envelope glycoconjugates of Mycobacterium tuberculosisBiosynthesis of a water-soluble lipid I analogue and a convenient assay for translocase I.An update on the use of rifapentine for tuberculosis therapy.Discovery of a capuramycin analog that kills nonreplicating Mycobacterium tuberculosis and its synergistic effects with translocase I inhibitorsAntitubercular Nanocarrier Combination Therapy: Formulation Strategies and in Vitro Efficacy for Rifampicin and SQ641.The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE.Fluorescence-based assay for polyprenyl phosphate-GlcNAc-1-phosphate transferase (WecA) and identification of novel antimycobacterial WecA inhibitors.New drugs and regimens for treatment of TB.A biocatalytic approach to capuramycin analogues by exploiting a substrate permissive N-transacylase CapW.Insights on how the Mycobacterium tuberculosis heme uptake pathway can be used as a drug target.Progress in targeting cell envelope biogenesis in Mycobacterium tuberculosis.Reconsidering some approved antimicrobial agents for tuberculosis.Therapeutic efficacy of SQ641-NE against Mycobacterium tuberculosis.Recent derivatives from smaller classes of fermentation-derived antibacterials.Antimycobacterial drugs currently in Phase II clinical trials and preclinical phase for tuberculosis treatment.The anti-tuberculosis agents under development and the challenges ahead.Mycobacterial cell wall biosynthesis: a multifaceted antibiotic target.Chemical modification of capuramycins to enhance antibacterial activityFunctional and kinetic analysis of the phosphotransferase CapP conferring selective self-resistance to capuramycin antibiotics.In vitro antimicrobial activities of capuramycin analogues against non-tuberculous mycobacteriaSelf-nanoemulsifying drug-delivery systems for potentiated anti-inflammatory activity of diacereinSpray Drying Strategies to Stop Tuberculosis
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P2860
Activity of SQ641, a capuramycin analog, in a murine model of tuberculosis
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Activity of SQ641, a capuramycin analog, in a murine model of tuberculosis
@en
Activity of SQ641, a capuramycin analog, in a murine model of tuberculosis.
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type
label
Activity of SQ641, a capuramycin analog, in a murine model of tuberculosis
@en
Activity of SQ641, a capuramycin analog, in a murine model of tuberculosis.
@nl
prefLabel
Activity of SQ641, a capuramycin analog, in a murine model of tuberculosis
@en
Activity of SQ641, a capuramycin analog, in a murine model of tuberculosis.
@nl
P2093
P2860
P356
P1476
Activity of SQ641, a capuramycin analog, in a murine model of tuberculosis
@en
P2093
Boris V Nikonenko
Carol A Nacy
Elena Bogatcheva
Marina Protopopova
Venkata M Reddy
P2860
P304
P356
10.1128/AAC.00366-09
P407
P577
2009-05-04T00:00:00Z