Rapid, simple in vivo screen for new drugs active against Mycobacterium tuberculosis
about
Protective immunity to Mycobacterium tuberculosis infection by chemokine and cytokine conditioned CFP-10 differentiated dendritic cellsDiscovery and development of SQ109: a new antitubercular drug with a novel mechanism of action.Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines.Identification of new diamine scaffolds with activity against Mycobacterium tuberculosis.Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis.Identification of SQ609 as a lead compound from a library of dipiperidines.How "humane" is your endpoint? Refining the science-driven approach for termination of animal studies of chronic infection.Comparative studies evaluating mouse models used for efficacy testing of experimental drugs against Mycobacterium tuberculosis.Mycobacterium tuberculosis embB codon 306 mutations confer moderately increased resistance to ethambutol in vitro and in vivo.Drug therapy of experimental tuberculosis (TB): improved outcome by combining SQ109, a new diamine antibiotic, with existing TB drugsInfluence of vehicles used for oral dosing of test molecules on the progression of Mycobacterium tuberculosis infection in mice.Activity of SQ641, a capuramycin analog, in a murine model of tuberculosisEvaluation of in vivo antimycobacterial activity of some folklore medicinal plants and enumeration of colony forming unit in murine model.Toll-like receptor 2 and DC-SIGNR1 differentially regulate suppressors of cytokine signaling 1 in dendritic cells during Mycobacterium tuberculosis infection.Multi-step usage of in vivo models during rational drug design and discovery.The anti-tuberculosis agents under development and the challenges ahead.Anti-Mycobacterium activity of microbial peptides in a silkworm infection model with Mycobacterium smegmatis.In Vitro Activity of 3-Triazeneindoles against Mycobacterium tuberculosis and Mycobacterium avium.A short-term model for preliminary screening of potential anti-tubercular compounds.Biological evaluation of novel curcumin-pyrazole-mannich derivative active against drug-resistant Mycobacterium tuberculosis.
P2860
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P2860
Rapid, simple in vivo screen for new drugs active against Mycobacterium tuberculosis
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Rapid, simple in vivo screen for new drugs active against Mycobacterium tuberculosis
@en
Rapid, simple in vivo screen for new drugs active against Mycobacterium tuberculosis.
@nl
type
label
Rapid, simple in vivo screen for new drugs active against Mycobacterium tuberculosis
@en
Rapid, simple in vivo screen for new drugs active against Mycobacterium tuberculosis.
@nl
prefLabel
Rapid, simple in vivo screen for new drugs active against Mycobacterium tuberculosis
@en
Rapid, simple in vivo screen for new drugs active against Mycobacterium tuberculosis.
@nl
P2093
P2860
P1476
Rapid, simple in vivo screen for new drugs active against Mycobacterium tuberculosis
@en
P2093
Boris V Nikonenko
Carol A Nacy
Rowena Samala
P2860
P304
P356
10.1128/AAC.48.12.4550-4555.2004
P407
P577
2004-12-01T00:00:00Z