Functional characterization of human variants of the mu-opioid receptor gene
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The role of the Asn40Asp polymorphism of the mu opioid receptor gene (OPRM1) on alcoholism etiology and treatment: a critical reviewUnidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioidsA heroin addiction severity-associated intronic single nucleotide polymorphism modulates alternative pre-mRNA splicing of the μ opioid receptor gene OPRM1 via hnRNPH interactions.How to design an opioid drug that causes reduced tolerance and dependence.Low frequency genetic variants in the μ-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine.Examining the role of mu opioid receptor endocytosis in the beneficial and side-effects of prolonged opioid use: from a symposium on new concepts in mu-opioid pharmacologyBuprenorphine signalling is compromised at the N40D polymorphism of the human μ opioid receptor in vitroCellular signalling of non-synonymous single-nucleotide polymorphisms of the human μ-opioid receptor (OPRM1)A C17T polymorphism in the mu opiate receptor is associated with quantitative measures of drug use in African American women.Genotyping test with clinical factors: better management of acute postoperative pain?A6V polymorphism of the human μ-opioid receptor decreases signalling of morphine and endogenous opioids in vitro.The Opposing Roles of IVS2+691 CC Genotype and AC/AG Diplotype of 118A>G and IVS2+691G>C of OPRM1 Polymorphisms in Cold Pain Tolerance Among Opioid-Dependent Malay Males on Methadone TherapyMu opioid receptor (OPRM1) as a predictor of treatment outcome in opiate-dependent individuals of Arab descent.Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.The AC/AG Diplotype for the 118A>G and IVS2 + 691G>C Polymorphisms of OPRM1 Gene is Associated with Sleep Quality Among Opioid-Dependent Patients on Methadone Maintenance TherapyDifferential expression and HIV-1 regulation of μ-opioid receptor splice variants across human central nervous system cell types.Association of morphine-induced analgesic tolerance with changes in gene expression of GluN1 and MOR1 in rat spinal cord and midbrain.Epigenetics of µ-opioid receptors: intersection with HIV-1 infection of the central nervous system.Evidence from basic research for opioid combinations.Clinical Implications of Opioid Pharmacogenomics in Patients With Cancer.A multicenter study of attitudinal barriers to cancer pain management.Elucidation of mu-Opioid Gene Structure: How Genetics Can Help Predict Responses to Opioids.The genetic influences on oxycodone response characteristics in human experimental pain.Reverse of Acute and Chronic Morphine Tolerance by Lithocholic Acid via Down-Regulating UGT2B7.Morphine-induced internalization of the L83I mutant of the rat μ-opioid receptorThe rare Arg181Cys mutation in the μ opioid receptor can abolish opioid responses.Social hedonic capacity is associated with the A118G polymorphism of the mu-opioid receptor gene (OPRM1) in adult healthy volunteers and psychiatric patients.Pharmacogenetics of opiates in clinical practice: the visible tip of the iceberg.
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Functional characterization of human variants of the mu-opioid receptor gene
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Functional characterization of human variants of the mu-opioid receptor gene
@en
Functional characterization of human variants of the mu-opioid receptor gene.
@nl
type
label
Functional characterization of human variants of the mu-opioid receptor gene
@en
Functional characterization of human variants of the mu-opioid receptor gene.
@nl
prefLabel
Functional characterization of human variants of the mu-opioid receptor gene
@en
Functional characterization of human variants of the mu-opioid receptor gene.
@nl
P2093
P2860
P356
P1476
Functional characterization of human variants of the mu-opioid receptor gene
@en
P2093
Ajay Ravindranathan
Geoff Joslyn
Jennifer L Whistler
Margaret Robertson
Raymond L White
P2860
P304
10811-10816
P356
10.1073/PNAS.0904509106
P407
P577
2009-06-15T00:00:00Z