Design of beta-hairpin peptidomimetics that inhibit binding of alpha-helical HIV-1 Rev protein to the rev response element RNA.
about
Essential structural requirements for specific recognition of HIV TAR RNA by peptide mimetics of Tat proteinApproaches to Validate and Manipulate RNA Targets with Small Molecules in CellsConstraining cyclic peptides to mimic protein structure motifs.Two-dimensional combinatorial screening identifies specific 6'-acylated kanamycin A- and 6'-acylated neamine-RNA hairpin interactions.Measuring cooperative Rev protein-protein interactions on Rev responsive RNA by fluorescence resonance energy transfer.Identification of benzenesulfonamide quinoline derivatives as potent HIV-1 replication inhibitors targeting Rev protein.Defining RNA-Small Molecule Affinity Landscapes Enables Design of a Small Molecule Inhibitor of an Oncogenic Noncoding RNAA Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing.N-Methylation as a Strategy for Enhancing the Affinity and Selectivity of RNA-binding Peptides: Application to the HIV-1 Frameshift-Stimulating RNA.γ-AApeptides bind to RNA by mimicking RNA-binding proteins.Multivalent binding oligomers inhibit HIV Tat-TAR interaction critical for viral replication.Strategies for the design of RNA-binding small molecules.RNA triplexes: from structural principles to biological and biotech applications.Positional effects of click cyclization on β-hairpin structure, stability, and function.Molecular dynamics and MM/GBSA-integrated protocol probing the correlation between biological activities and binding free energies of HIV-1 TAR RNA inhibitors.Structure-activity studies on the fluorescent indicator in a displacement assay for the screening of small molecules binding to RNA.A Thioether-Stabilized d-Proline-l-Proline-Induced β-Hairpin Peptide of Defensin Segment Increases Its Anti-Candida albicans Ability.Design of photocontrolled RNA-binding peptidomimetics.
P2860
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P2860
Design of beta-hairpin peptidomimetics that inhibit binding of alpha-helical HIV-1 Rev protein to the rev response element RNA.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Design of beta-hairpin peptido ...... the rev response element RNA.
@en
Design of beta-hairpin peptido ...... the rev response element RNA.
@nl
type
label
Design of beta-hairpin peptido ...... the rev response element RNA.
@en
Design of beta-hairpin peptido ...... the rev response element RNA.
@nl
prefLabel
Design of beta-hairpin peptido ...... the rev response element RNA.
@en
Design of beta-hairpin peptido ...... the rev response element RNA.
@nl
P2093
P2860
P356
P1476
Design of beta-hairpin peptido ...... the rev response element RNA.
@en
P2093
Amy Davidson
Gabriele Varani
John A Robinson
Kerstin Moehle
Krystyna Patora
Zafiria Athanassiou
P2860
P304
P356
10.1002/ANIE.200702801
P407
P577
2007-01-01T00:00:00Z