A single charged voltage sensor is capable of gating the Shaker K+ channel
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The opening of the two pores of the Hv1 voltage-gated proton channel is tuned by cooperativityVoltage gated ion channel function: gating, conduction, and the role of water and protonsSodium leak channels in neuronal excitability and rhythmic behaviorsA distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1aA linkage analysis toolkit for studying allosteric networks in ion channels.Operation of the voltage sensor of a human voltage- and Ca2+-activated K+ channel.Coupling and cooperativity in voltage activation of a limited-state BK channel gating in saturating Ca2+.Arrangement of Kv1 alpha subunits dictates sensitivity to tetraethylammonium.Phosphatidylinositol-4,5-bisphosphate (PIP(2)) stabilizes the open pore conformation of the Kv11.1 (hERG) channelThe contribution of individual subunits to the coupling of the voltage sensor to pore opening in Shaker K channels: effect of ILT mutations in heterotetramers.The electrically silent Kv6.4 subunit confers hyperpolarized gating charge movement in Kv2.1/Kv6.4 heterotetrameric channels.Alkanols inhibit voltage-gated K(+) channels via a distinct gating modifying mechanism that prevents gate opening.Tetrameric assembly of KvLm K+ channels with defined numbers of voltage sensors.Intersubunit Concerted Cooperative and cis-Type Mechanisms Modulate Allosteric Gating in Two-Pore-Domain Potassium Channel TREK-2.Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels.Consequences of dimerization of the voltage-gated proton channel.Electrically silent Kv subunits: their molecular and functional characteristics.Modeling ion channels: past, present, and futureIndependent and cooperative motions of the Kv1.2 channel: voltage sensing and gating.Unlocking the mechanisms of HCN channel gating with locked-open and locked-closed channels.Enhancement of Closed-State Inactivation by Neutralization of S4 Arginines in Domain IV of a Sodium Channel.What activates inactivation?Uncooperative voltage sensors.Upward movement of IS4 and IIIS4 is a rate-limiting stage in Cav1.2 activation.The pain receptor TRPV1 displays agonist-dependent activation stoichiometry.Key role of segment IS4 in Cav1.2 inactivation: link between activation and inactivation.Grafting voltage and pharmacological sensitivity in potassium channelsKCNQ1 channels do not undergo concerted but sequential gating transitions in both the absence and the presence of KCNE1 proteinNeutralisation of a single voltage sensor affects gating determinants in all four pore-forming S6 segments of Ca(V)1.2: a cooperative gating model.Mode shift of the voltage sensors in Shaker K+ channels is caused by energetic coupling to the pore domainGating energetics of a voltage-dependent K+ channel pore domain.Heat activation is intrinsic to the pore domain of TRPV1.Inactivation gating of Kv7.1 channels does not involve concerted cooperative subunit interactions.Inhibition of the K+ conductance and Cole-Moore shift of the oncogenic Kv10.1 channel by amiodarone.Stabilization of the Activated hERG Channel Voltage Sensor by Depolarization Involves the S4-S5 Linker.Position-dependent attenuation by Kv1.6 of N-type inactivation of Kv1.4-containing channels.Gating Modulation of the Tumor-Related Kv10.1 Channel by Mibefradil.
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A single charged voltage sensor is capable of gating the Shaker K+ channel
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2009
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
A single charged voltage sensor is capable of gating the Shaker K+ channel
@en
A single charged voltage sensor is capable of gating the Shaker K+ channel.
@nl
type
label
A single charged voltage sensor is capable of gating the Shaker K+ channel
@en
A single charged voltage sensor is capable of gating the Shaker K+ channel.
@nl
prefLabel
A single charged voltage sensor is capable of gating the Shaker K+ channel
@en
A single charged voltage sensor is capable of gating the Shaker K+ channel.
@nl
P2860
P356
P1476
A single charged voltage sensor is capable of gating the Shaker K+ channel
@en
P2093
Dominique G Gagnon
Francisco Bezanilla
P2860
P304
P356
10.1085/JGP.200810082
P577
2009-05-01T00:00:00Z