A structural model for K2P potassium channels based on 23 pairs of interacting sites and continuum electrostatics.
about
Gating of a pH-sensitive K(2P) potassium channel by an electrostatic effect of basic sensor residues on the selectivity filterOne SUMO is sufficient to silence the dimeric potassium channel K2P1SUMOylation silences heterodimeric TASK potassium channels containing K2P1 subunits in cerebellar granule neurons.Multi-scale electrophysiology modeling: from atom to organA new TASK for Dipeptidyl Peptidase-like Protein 6.Molecular aspects of structure, gating, and physiology of pH-sensitive background K2P and Kir K+-transport channels.Charge substitution for a deep-pore residue reveals structural dynamics during BK channel gating.Multiple modalities converge on a common gate to control K2P channel function.External Ba2+ block of the two-pore domain potassium channel TREK-1 defines conformational transition in its selectivity filter.Molecular regulations governing TREK and TRAAK channel functions.Breathing Stimulant Compounds Inhibit TASK-3 Potassium Channel Function Likely by Binding at a Common Site in the Channel Pore.Q/R site interactions with the M3 helix in GluK2 kainate receptor channels revealed by thermodynamic mutant cycles.Potassium channels in peripheral pain pathways: expression, function and therapeutic potential.Gating of two pore domain potassium channels.A Role for K2P Channels in the Operation of Somatosensory NociceptorsK(+) channels: function-structural overview.The pore structure and gating mechanism of K2P channels.A specific two-pore domain potassium channel blocker defines the structure of the TASK-1 open pore.Complex Locomotion Behavior Changes Are Induced in Caenorhabditis elegans by the Lack of the Regulatory Leak K+ Channel TWK-7.Grafting voltage and pharmacological sensitivity in potassium channelsK2P potassium channels, mysterious and paradoxically exciting.An extracellular ion pathway plays a central role in the cooperative gating of a K(2P) K+ channel by extracellular pH.Understanding ion channels using computational approaches.
P2860
Q28476814-9888655D-4E39-45BA-A20E-94736BE7F010Q30495084-720C073F-6158-4C9B-8498-35AA7FF203A8Q30561107-4B8EA682-9190-4855-967D-C71A24F428C2Q33922826-DA64E211-4908-4592-BB71-60EC9CCEF3C4Q34674195-7B964D8E-7412-4775-AB46-2E6E93ED4119Q34800154-DBF0498E-6E6F-4202-8B34-09315C03016EQ35145307-DDAADCED-B3CC-4024-8014-A04127FC42E4Q35236043-9CAA652B-E6C3-49DF-9978-4D438A60121BQ35562711-A9B55C48-F273-4FED-8515-0D89EF6C0D47Q35693711-161475BC-BBDE-4311-B53C-7B25DFB7386AQ36186112-EB1088D3-F840-494C-91A8-DFD5B916DDBAQ37121982-E6ED32D0-F7D9-49C9-A177-132CE99C2425Q37362041-8DDD9B0F-44F5-4097-9DD0-9F2C37536258Q37766696-2AAECB22-AE30-44E0-BBDF-452FBA9298B1Q37992048-3A68A685-AD2C-4897-BAA7-5A6F85A8B4B4Q38110757-277F754F-AF83-43F1-8F1A-CD80841A1168Q38576884-8ACD615A-938F-41BF-90D8-9F44C076F2BEQ39777149-2D68934F-75C5-47AC-86E4-2D4990CA9EAAQ41642422-BE9D9A16-C329-4F69-A374-FF8BAD5F847DQ42381325-AB7C0172-D776-41F9-BE6C-50BDF5A188ABQ42767738-AA9ACB71-BF41-4A4A-998C-DDE8EFD1032CQ43240562-93793BD4-2E4A-4B0E-B8D4-1688D2C51B3CQ44764966-BE65D6AF-B9A9-48FF-9D5F-6BA457210C92
P2860
A structural model for K2P potassium channels based on 23 pairs of interacting sites and continuum electrostatics.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A structural model for K2P pot ...... and continuum electrostatics.
@en
A structural model for K2P pot ...... and continuum electrostatics.
@nl
type
label
A structural model for K2P pot ...... and continuum electrostatics.
@en
A structural model for K2P pot ...... and continuum electrostatics.
@nl
prefLabel
A structural model for K2P pot ...... and continuum electrostatics.
@en
A structural model for K2P pot ...... and continuum electrostatics.
@nl
P2093
P2860
P356
P1476
A structural model for K2P pot ...... and continuum electrostatics.
@en
P2093
Albert Y Lau
Ashley Sullivan
Astrid Kollewe
Benoît Roux
Steve A N Goldstein
P2860
P356
10.1085/JGP.200910235
P577
2009-07-01T00:00:00Z