igr Genes and Mycobacterium tuberculosis cholesterol metabolism - Wikidata - awgldk - TriplyDB

igr Genes and Mycobacterium tuberculosis cholesterol metabolism

igr Genes and Mycobacterium tuberculosis cholesterol metabolism

http://www.wikidata.org/entity/Q37302014

about

High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism Pathogen roid rage: cholesterol utilization by Mycobacterium tuberculosis Mycobacterium tuberculosis utilizes a unique heterotetrameric structure for dehydrogenation of the cholesterol side chain Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one Mycobacterial cytochrome p450 125 (cyp125) catalyzes the terminal hydroxylation of c27 steroids Mycobacterium tuberculosis: success through dormancy Structural and Biochemical Characterization of Mycobacterium tuberculosis CYP142: EVIDENCE FOR MULTIPLE CHOLESTEROL 27-HYDROXYLASE ACTIVITIES IN A HUMAN PATHOGEN Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1 A highly conserved mycobacterial cholesterol catabolic pathway New insights into TB physiology suggest untapped therapeutic opportunities Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations Functional redundancy of steroid C26-monooxygenase activity in Mycobacterium tuberculosis revealed by biochemical and genetic analyses Pathway profiling in Mycobacterium tuberculosis: elucidation of cholesterol-derived catabolite and enzymes that catalyze its metabolism Cholesterol utilization in mycobacteria is controlled by two TetR-type transcriptional regulators: kstR and kstR2 The Mycobacterium tuberculosis regulatory network and hypoxia Non-coding RNA and its potential role in Mycobacterium tuberculosis pathogenesis Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 α2β2 Acyl-CoA Dehydrogenase Initiates β-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA.The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis.Mycobacterial gene cuvA is required for optimal nutrient utilization and virulence A thiolase of Mycobacterium tuberculosis is required for virulence and production of androstenedione and androstadienedione from cholesterol.Functional genetic diversity among Mycobacterium tuberculosis complex clinical isolates: delineation of conserved core and lineage-specific transcriptomes during intracellular survival The Mycobacterium avium ssp. paratuberculosis specific mptD gene is required for maintenance of the metabolic homeostasis necessary for full virulence in mouse infections.Mycobacterium tuberculosis wears what it eats Draft genome sequence of Gordonia neofelifaecis NRRL B-59395, a cholesterol-degrading actinomycete Slow growth of Mycobacterium tuberculosis at acidic pH is regulated by phoPR and host-associated carbon sources.Microbial steroid transformations: current state and prospects.Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infection Mycobacterium tuberculosis cholesterol catabolism requires a new class of acyl coenzyme A dehydrogenase.Cholesterol ester oxidation by mycobacterial cytochrome P450.A distinct MaoC-like enoyl-CoA hydratase architecture mediates cholesterol catabolism in Mycobacterium tuberculosis.The role of 3-ketosteroid 1(2)-dehydrogenase in the pathogenicity of Mycobacterium tuberculosis.Mycobacterium tuberculosis strains lacking surface lipid phthiocerol dimycocerosate are susceptible to killing by an early innate host response.Cholesterol is not an essential source of nutrition for Mycobacterium tuberculosis during infection FadA5 a thiolase from Mycobacterium tuberculosis: a steroid-binding pocket reveals the potential for drug development against tuberculosis Cholesterol oxidase is indispensable in the pathogenesis of Mycobacterium tuberculosis Cytochrome P450 125 (CYP125) catalyses C26-hydroxylation to initiate sterol side-chain degradation in Rhodococcus jostii RHA1.Comprehensive insights into transcriptional adaptation of intracellular mycobacteria by microbe-enriched dual RNA sequencing Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis.The tuberculosis drug discovery and development pipeline and emerging drug targets.Deletion of cyp125 Confers Increased Sensitivity to Azoles in Mycobacterium tuberculosis.

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igr Genes and Mycobacterium tuberculosis cholesterol metabolism

http://www.wikidata.org/entity/Q37302014

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on 19 June 2009

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

igr Genes and Mycobacterium tuberculosis cholesterol metabolism

@en

igr Genes and Mycobacterium tuberculosis cholesterol metabolism.

@nl

type

label

igr Genes and Mycobacterium tuberculosis cholesterol metabolism

@en

igr Genes and Mycobacterium tuberculosis cholesterol metabolism.

@nl

prefLabel

igr Genes and Mycobacterium tuberculosis cholesterol metabolism

@en

igr Genes and Mycobacterium tuberculosis cholesterol metabolism.

@nl

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Journal of Bacteriology

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igr Genes and Mycobacterium tuberculosis cholesterol metabolism

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P2093

Amit K Pandey

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Christopher M Sassetti

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David R Sherman

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Jennifer C Chang

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Nada S Harik

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Wendy P Gill

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P2860

Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence

Biochemical differentiation of Mycobacterium tuberculosis grown in vivo and in vitro

Genes required for mycobacterial growth defined by high density mutagenesis

Rv1106c from Mycobacterium tuberculosis is a 3beta-hydroxysteroid dehydrogenase

Cholesterol oxidase is required for virulence of Mycobacterium tuberculosis

A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages

Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages

Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase

P304

5232-5239

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scholarly article

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10.1128/JB.00452-09

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16

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191

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Maurine D Miner

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2009-06-19T00:00:00Z

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19542286

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P921

Akafuba bulwadde

Mycobacterium tuberculosis

P932

2725594

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