CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. - Wikidata - awgldk - TriplyDB

CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.

CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.

http://www.wikidata.org/entity/Q37305045

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CD47: A Cell Surface Glycoprotein Which Regulates Multiple Functions of Hematopoietic Cells in Health and Disease Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47 Perspectives on anti-CD47 antibody treatment for experimental cancer Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response The CD47-SIRPα pathway in cancer immune evasion and potential therapeutic implications Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies.Therapeutic opportunities for targeting the ubiquitous cell surface receptor CD47 Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy Thrombospondin-1 signaling through CD47 inhibits self-renewal by regulating c-Myc and other stem cell transcription factors Stem cell technology in breast cancer: current status and potential applications Multiple myeloma cancer stem cells Cancer Stem Cells and Macrophages: Implications in Tumor Biology and Therapeutic Strategies Cellular and molecular biology of small cell lung cancer: an overview Interplay between Cellular and Molecular Inflammatory Mediators in Lung Cancer Humanized hemato-lymphoid system mice Therapies targeting cancer stem cells: Current trends and future challenges Concepts and mechanisms underlying chemotherapy induced immunogenic cell death: impact on clinical studies and considerations for combined therapies Prognostic and Predictive Value of DAMPs and DAMP-Associated Processes in Cancer Increased Oxidative Stress as a Selective Anticancer Therapy Cancer stem cells--important players in tumor therapy resistance Harnessing the antitumor potential of macrophages for cancer immunotherapy Reactive oxygen species in cancer stem cells The complex and central role of interferon-γ in graft-versus-host disease and graft-versus-tumor activity Concise review: Leukemia stem cells in personalized medicine Childhood acute myeloid leukaemia Macrophages: gatekeepers of tissue integrity Targeting the innate immune system as immunotherapy for acute myeloid leukemia Animal models of leukemia: any closer to the real thing?An advanced preclinical mouse model for acute myeloid leukemia using patients' cells of various genetic subgroups and in vivo bioluminescence imaging Polymorphisms in the Human Inhibitory Signal-regulatory Protein Do Not Affect Binding to Its Ligand CD47 Targeted immunotherapy for acute myeloid leukemia Update on acute myeloid leukemia stem cells: New discoveries and therapeutic opportunities Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer Minimal Residual Disease in Acute Myeloid Leukemia of Adults: Determination, Prognostic Impact and Clinical Applications DNMT3A and TET2 in the Pre-Leukemic Phase of Hematopoietic Disorders Cancer stem cells in basic science and in translational oncology: can we translate into clinical application?Stem cell applications for pathologies of the urinary bladder Chemotherapy targeting cancer stem cells

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CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.

http://www.wikidata.org/entity/Q37305045

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on July 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

CD47 is an adverse prognostic ...... e myeloid leukemia stem cells.

@en

CD47 is an adverse prognostic ...... e myeloid leukemia stem cells.

@nl

type

label

CD47 is an adverse prognostic ...... e myeloid leukemia stem cells.

@en

CD47 is an adverse prognostic ...... e myeloid leukemia stem cells.

@nl

prefLabel

CD47 is an adverse prognostic ...... e myeloid leukemia stem cells.

@en

CD47 is an adverse prognostic ...... e myeloid leukemia stem cells.

@nl

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J.CELL.2009.05.045

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CD47 is an adverse prognostic ...... te myeloid leukemia stem cells

@en

P2093

Irving L Weissman

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Mark P Chao

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Nico van Rooijen

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Ravindra Majeti

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Siddhartha Jaiswal

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Wendy W Pang

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P2860

Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood

AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation

Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia.

Stem cells, cancer, and cancer stem cells

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Role of CD47 as a marker of self on red blood cells

Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterreceptor CD47

The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

CD47 ligation induces caspase-independent cell death in chronic lymphocytic leukemia

Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461)

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286-299

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10.1016/J.CELL.2009.05.045

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2

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138

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Kenneth D Gibbs

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2009-07-01T00:00:00Z

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26695308

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19632179

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