Recent advances in the chemistry and biology of naturally occurring antibiotics. - Wikidata - awgldk - TriplyDB

Recent advances in the chemistry and biology of naturally occurring antibiotics.

Recent advances in the chemistry and biology of naturally occurring antibiotics.

http://www.wikidata.org/entity/Q37313939

about

Radical-mediated enzymatic carbon chain fragmentation-recombination Identification of distinct thiopeptide-antibiotic precursor lead compounds using translation machinery assays Origins of regioselectivity of Diels-Alder reactions for the synthesis of bisanthraquinone antibiotic BE-43472B.Postgenomic strategies in antibacterial drug discovery.Probing translation with small-molecule inhibitors Thoughts and facts about antibiotics: where we are now and where we are heading.Synthesis and evaluation of selected key methyl ether derivatives of vancomycin aglycon.Total synthesis and structural revision of viridicatumtoxin B.Capturing the essence of organic synthesis: from bioactive natural products to designed molecules in today's medicine.The evolving role of chemical synthesis in antibacterial drug discovery.Total Synthesis of Nosiheptide.Differential effects of thiopeptide and orthosomycin antibiotics on translational GTPases.Total synthesis and biological evaluation of tyroscherin.Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.A Facile Semi-Synthetic Approach towards Halogen-Substituted Aminobenzoic Acid Analogues of Platensimycin.How thiostrepton was made in the laboratory.Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus.Total synthesis and absolute configuration of the bisanthraquinone antibiotic BE-43472B The art of total synthesis through cascade reactions Total synthesis and biological evaluation of (+)- and (-)-bisanthraquinone antibiotic BE-43472B and related compounds.Total synthesis of platensimycin and related natural products Development of novel drugs from marine surface associated microorganisms.Natural products containing a diazo group.Regio- and chemoselective metalation of arenes and heteroarenes using hindered metal amide bases.Small organometallic compounds as antibacterial agents.Biosynthesis of thiopeptide antibiotics and their pathway engineering.Developing new antibacterials through natural product research.Total synthesis of natural products using hypervalent iodine reagents.YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function.Synthesis of Antibiotics.Synthesis and study of antibacterial activities of antibacterial glycopeptide antibiotics conjugated with benzoxaboroles.Synthesis of the heterocyclic core of the D-series GE2270.Ti(Oi-Pr)4-promoted photoenolization Diels-Alder reaction to construct polycyclic rings and its synthetic applications.Mutagenesis of NosM Leader Peptide Reveals Important Elements in Nosiheptide Biosynthesis Rhodium-catalyzed asymmetric enyne cycloisomerization of terminal alkynes and formal total synthesis of (-)-platensimycin.Total synthesis and biological evaluation of (-)-atrop-abyssomicin C.Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation.Fungal biotransformation of tanshinone results in [4+2] cycloaddition with sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity.Alanine scan of the peptide antibiotic feglymycin: assessment of amino acid side chains contributing to antimicrobial activity.Total synthesis of (-)-platensimycin by advancing oxocarbenium- and iminium-mediated catalytic methods.

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Recent advances in the chemistry and biology of naturally occurring antibiotics.

http://www.wikidata.org/entity/Q37313939

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on January 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Recent advances in the chemistry and biology of naturally occurring antibiotics.

@en

Recent advances in the chemistry and biology of naturally occurring antibiotics.

@nl

type

label

Recent advances in the chemistry and biology of naturally occurring antibiotics.

@en

Recent advances in the chemistry and biology of naturally occurring antibiotics.

@nl

prefLabel

Recent advances in the chemistry and biology of naturally occurring antibiotics.

@en

Recent advances in the chemistry and biology of naturally occurring antibiotics.

@nl

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Angewandte Chemie International Edition

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Recent advances in the chemistry and biology of naturally occurring antibiotics.

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Anthony A Estrada

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David J Edmonds

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Jason S Chen

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K C Nicolaou

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THE STRUCTURAL BIOLOGY OF TYPE II FATTY ACID BIOSYNTHESIS

Discovery of FabH/FabF inhibitors from natural products.

Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance

Fatty acid synthesis: a potential selective target for antineoplastic therapy

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells

Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

Total synthesis of lysobactin

Structure of an EF-Tu complex with a thiazolyl peptide antibiotic determined at 2.35 A resolution: atomic basis for GE2270A inhibition of EF-Tu

Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism

X-Ray Crystal Structure of Mycobacterium tuberculosis β-Ketoacyl Acyl Carrier Protein Synthase II (mtKasB)

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660-719

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scholarly article

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10.1002/ANIE.200801695

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4

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48

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2009-01-01T00:00:00Z

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23765240

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19130444

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2730216

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