Design, Synthesis, and Anti-leukemic Activity of Stereochemically Defined Constrained Analogs of FTY720 (Gilenya).
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The emerging role of FTY720 (Fingolimod) in cancer treatmentAttacking the supply wagons to starve cancer cells to death.Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation.The antineoplastic properties of FTY720: evidence for the repurposing of fingolimod.Azacyclic FTY720 Analogues That Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill Cancer Cells in Vivo.Cloning and characterization of three ketoreductases from soil metagenome for preparing optically active alcohols.
P2860
Design, Synthesis, and Anti-leukemic Activity of Stereochemically Defined Constrained Analogs of FTY720 (Gilenya).
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Design, Synthesis, and Anti-le ...... d Analogs of FTY720 (Gilenya).
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Design, Synthesis, and Anti-le ...... d Analogs of FTY720 (Gilenya).
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type
label
Design, Synthesis, and Anti-le ...... d Analogs of FTY720 (Gilenya).
@en
Design, Synthesis, and Anti-le ...... d Analogs of FTY720 (Gilenya).
@nl
prefLabel
Design, Synthesis, and Anti-le ...... d Analogs of FTY720 (Gilenya).
@en
Design, Synthesis, and Anti-le ...... d Analogs of FTY720 (Gilenya).
@nl
P2093
P2860
P356
P1476
Design, Synthesis, and Anti-le ...... d Analogs of FTY720 (Gilenya).
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P2093
Aimee L Edinger
Alison N McCracken
Rebecca Fransson
Ryan J McMonigle
Stephen Hanessian
P2860
P356
10.1021/ML4002425
P577
2013-10-01T00:00:00Z