Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module. - Wikidata - awgldk - TriplyDB

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module.

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module.

http://www.wikidata.org/entity/Q37333588

about

Scribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of Akt Epithelial cell polarity: a major gatekeeper against cancer?Differential expression of PDZ domain-containing proteins in human diseases - challenging topics and novel issues Uncorking gastrulation: the morphogenetic movement of bottle cells Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland Lgl2 executes its function as a tumor suppressor by regulating ErbB signaling in the zebrafish epidermis Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule Aberrant overexpression of the cell polarity module scribble in human cancer DLG5 in cell polarity maintenance and cancer development Loss of the tumor suppressor Pten promotes proliferation of Drosophila melanogaster cells in vitro and gives rise to continuous cell lines Involvement of Girdin in the determination of cell polarity during cell migration Discovery and confirmation of ligand binding specificities of the Schistosoma japonicum polarity protein Scribble Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded A genome-wide association study identifies susceptibility loci for Wilms tumor The invasive capacity of HPV transformed cells requires the hDlg-dependent enhancement of SGEF/RhoG activity.Protein kinase Cα promotes cell migration through a PDZ-dependent interaction with its novel substrate discs large homolog 1 (DLG1)Scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs.Novel mechanism of tumor suppression by polarity gene discs large 1 (DLG1) revealed in a murine model of pediatric B-ALL.Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium.Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells.Ras transformation uncouples the kinesin-coordinated cellular nutrient response Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway.The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila Differential regulation of cell-cell contact, invasion and anoikis by hScrib and hDlg in keratinocytes Epithelial junctions maintain tissue architecture by directing planar spindle orientation.Drosophila melanogaster as a model for human intestinal infection and pathology.Hugl1 and Hugl2 in mammary epithelial cells: polarity, proliferation, and differentiation.Detection of in situ protein-protein complexes at the Drosophila larval neuromuscular junction using proximity ligation assay.A novel interaction between hScrib and PP1γ downregulates ERK signaling and suppresses oncogene-induced cell transformation.Hippo signaling: growth control and beyond.Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery.Mutations in planar cell polarity gene SCRIB are associated with spina bifida.The Garz Sec7 domain guanine nucleotide exchange factor for Arf regulates salivary gland development in Drosophila Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis.Friend or foe: Endoplasmic reticulum protein 29 (ERp29) in epithelial cancer.Cell biological regulation of division fate in vertebrate neuroepithelial cells.Spectrin binding motifs regulate Scribble cortical dynamics and polarity function.Discs large in the Drosophila testis: an old player on a new task.

P2860

Q24307722-2244FCDC-00C0-4FB4-B322-68311B02EE96 Q24635870-4B38CED8-EDFA-4B9C-A81E-B4DB670932EA Q27015135-308D34A8-0854-471D-8C7E-1A21E885B173 Q27025175-C4174F25-4770-418C-A8AA-B1557B77C847 Q27315980-4FFE28F1-9E05-454A-BD5E-8F5BA8A7D709 Q27348603-7FDDEF36-5412-45FA-A535-AEA25B97847D Q27681660-5769579D-9958-4B5B-ACED-6FE3BBAE793B Q27698087-7600C832-A0BA-46B1-8D9D-F01545397E5E Q28236961-040DEAF0-E361-43A1-A673-4499ABCB99B5 Q28241647-7965F05F-40D5-47C7-B67A-3B003DD29BFF Q28480990-D3EB637A-39EB-4504-8078-9C98C9359436 Q28483426-FE084AB7-7A71-4E11-BD9B-C013BB5C4AC2 Q28538306-771BCDE9-3BC8-402F-8054-D798D45447B8 Q28752559-95FB67F4-4979-417A-85D4-F9A7511B8107 Q28943448-C65E3BDB-BD3E-40A1-85A6-9D25DADD55F8 Q30010159-193F501A-173C-4768-A3AC-4E4111F6B04C Q30010216-2592F04F-7477-4387-AF61-4E6070DE2B9E Q33506529-5BA833F1-467C-41B8-962C-F9D2086EF65E Q33551348-83DC56DE-7A7F-4F01-9A47-D8439717BD58 Q33556272-D4C84C31-0C34-49D4-B6E6-3469A4A992C8 Q33631023-D5563A0A-0EAC-470A-8D31-6FA389EC7D61 Q33972110-CE73D548-67F1-47A4-88FA-FBC85DEAF3F6 Q34034164-743D2D9B-2B9E-4D27-A3DC-8AE057F51C07 Q34093277-CD78214C-37E0-49B8-9D33-5FAB0415D256 Q34115445-9E360C20-B482-4D86-B556-3D53A389A6C7 Q34336084-4459BFBF-9087-4331-AAD9-5CAE0499D4A7 Q34358882-E7D0A822-72B2-4715-8047-ED1F7051618C Q34458779-48F35E55-E3FE-4869-B7A0-85A5F5C21F12 Q34460559-8715E69C-41E4-40B2-9ACA-01D27A6D1040 Q34461218-08328D90-5BD4-47CB-955C-DB3BAEA266A3 Q34566263-348B5E86-24F0-4002-8789-8E7094D4F99E Q34625638-C6FD738E-B264-4F47-AAFB-76D05F5E31A4 Q34858502-22F7EE56-69CC-4998-A390-F0BECD9D7E70 Q34902377-CC96BEFE-906E-40D4-AC71-E5A843480962 Q35049657-1AC9ECF6-196C-4945-B8C8-508ACCE1D470 Q35060075-388F0C18-DDD7-4087-BE7F-06D80F09982C Q35086896-E9EDA2EB-414C-4CDC-85A8-9686C42FB4B0 Q35116856-A317875F-D262-481F-A51B-F5429C764BD1 Q35149866-781352D4-4A8B-4265-A5CF-3CEC5E43DCAD Q35216611-1D05AE00-10DD-43AD-B7F5-B1F7BCB89976

P2860

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module.

http://www.wikidata.org/entity/Q37333588

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年学术文章

@wuu

2008年学术文章

@zh-cn

2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module.

@en

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module.

@nl

type

label

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module.

@en

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module.

@nl

prefLabel

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module.

@en

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module.

@nl

P1433

Q37333588-C34ACEEC-CB7F-4F2A-9D51-67790076314C

P1476

Q37333588-A1BEA25F-67E7-499E-95ED-0C097176C8DB

P2093

Q37333588-4303F80A-3C69-4A88-AF12-1088E4CF01E2

Q37333588-6F33B17C-8D82-4577-A947-72F492B760A6

Q37333588-7DBD84AD-86E8-4685-8A92-30259464C173

Q37333588-DD74852C-991B-4A63-93A3-A1DAA4B2C50F

P2860

Q37333588-00FBB0F2-D34C-4833-BB45-84A1683C5A02

Q37333588-0182EB1D-284E-4081-93E9-1D3FE178937F

Q37333588-02E6CD53-CA8D-4D4B-8A83-DF955A9C3962

Q37333588-03CCF51F-E8C8-4467-93EE-E4C3F5CCE94B

Q37333588-03CEA7E6-361C-4A1A-9F5D-C757E606921B

Q37333588-054ABDE0-87FB-4535-A71E-7F11CE39A82C

Q37333588-065AAC28-93E9-4B56-BAD4-A831343F7CA7

Q37333588-09840348-286E-4863-A263-CCADD54A3FE6

Q37333588-0A1CA288-266B-4093-A881-DAB0AD1252EA

Q37333588-0AED4744-A7F3-4DE8-AAF2-6FFA32E07BC7

P2888

Q37333588-0C3A1717-606D-415C-9832-4C62FC4440A2

P304

Q37333588-87D4DD62-C64F-4EDF-81DC-442EC1AE23E3

P31

Q37333588-4FBAD52D-49D9-43E3-86BD-D86708C5558E

P356

Q37333588-164A1F40-0685-4763-810E-F6C83B485A70

P407

Q37333588-E3F512D5-5C0E-4092-BF69-D0F0BD04A4D6

P433

Q37333588-64FB6DF9-0F49-44D9-9B0F-506D191442B8

P478

Q37333588-4CC49890-FD4A-4671-A4D4-80971E17EE9B

P50

Q37333588-3AACA1CE-0E0D-45AE-BDCB-7C1E740E3C7E

Q37333588-8F8FEDF6-EC39-453B-8409-679BAF760A96

P577

Q37333588-93673CA8-7D02-4BF5-8532-8AC518E888C4

P5875

Q37333588-E79FBA55-8FFB-4D86-9860-829D420A5B4B

P6179

Q37333588-B8551789-BEC8-4B3C-A26E-19923DC8F70A

P698

Q37333588-A84447F1-C52B-41D3-929B-05D2AFFECB12

P356

P1433

P1476

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module.

@en

P2093

A M Brumby

http://www.w3.org/2001/XMLSchema#string

N A Grzeschik

http://www.w3.org/2001/XMLSchema#string

P O Humbert

http://www.w3.org/2001/XMLSchema#string

R Galea

http://www.w3.org/2001/XMLSchema#string

P2860

The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase

The Hallmarks of Cancer

Mammalian Scribble forms a tight complex with the betaPIX exchange factor

Segregation of receptor and ligand regulates activation of epithelial growth factor receptor

Thyrotropin receptor trafficking relies on the hScrib-betaPIX-GIT1-ARF6 pathway

The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin

Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity

Human homolog of Drosophila tumor suppressor Scribble negatively regulates cell-cycle progression from G1 to S phase by localizing at the basolateral membrane in epithelial cells

Human homolog of disc-large is required for adherens junction assembly and differentiation of human intestinal epithelial cells

Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases

P2888

P304

6888-6907

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/ONC.2008.341

http://www.w3.org/2001/XMLSchema#string

P407

P433

55

http://www.w3.org/2001/XMLSchema#string

P478

27

http://www.w3.org/2001/XMLSchema#string

P50

Helena E. Richardson

P577

2008-11-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23493831

http://www.w3.org/2001/XMLSchema#string

P6179

1051979527

http://www.w3.org/2001/XMLSchema#string

P698

19029932

http://www.w3.org/2001/XMLSchema#string