Phospholipase C-gamma binds directly to the Na+/H+ exchanger 3 and is required for calcium regulation of exchange activity.

Phospholipase C-gamma binds directly to the Na+/H+ exchanger 3 and is required for calcium regulation of exchange activity.

Item
http://www.wikidata.org/entity/Q37339302
Reduced sodium/proton exchanger NHE3 activity causes congenital sodium diarrheaAdaptive GDDA-BLAST: fast and efficient algorithm for protein sequence embeddingGastrin induces sodium-hydrogen exchanger 3 phosphorylation and mTOR activation via a phosphoinositide 3-kinase-/protein kinase C-dependent but AKT-independent pathway in renal proximal tubule cells derived from a normotensive male human.Phosphatidylinositol 4,5-bisphosphate and loss of PLCgamma activity inhibit TRPM channels required for oscillatory Ca2+ signaling.PLC-γ directly binds activated c-Src, which is necessary for carbachol-mediated inhibition of NHE3 activity in Caco-2/BBe cellsNHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity.Effect of acute acid-base disturbances on the phosphorylation of phospholipase C-γ1 and Erk1/2 in the renal proximal tubule.Calmodulin kinase II constitutively binds, phosphorylates, and inhibits brush border Na+/H+ exchanger 3 (NHE3) by a NHERF2 protein-dependent process.Secretory diarrhoea: mechanisms and emerging therapies.Mechanisms of the regulation of the intestinal Na+/H+ exchanger NHE3Carbachol-mediated endocytosis of NHE3 involves a clathrin-independent mechanism requiring lipid rafts and Cdc42.Tyrosine phosphorylation-dependent activation of TRPC6 regulated by PLC-γ1 and nephrin: effect of mutations associated with focal segmental glomerulosclerosis.
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Phospholipase C-gamma binds directly to the Na+/H+ exchanger 3 and is required for calcium regulation of exchange activity.

Item
http://www.wikidata.org/entity/Q37339302
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Phospholipase C-gamma binds di ...... gulation of exchange activity.
@en
Phospholipase C-gamma binds di ...... gulation of exchange activity.
@nl
type
label
Phospholipase C-gamma binds di ...... gulation of exchange activity.
@en
Phospholipase C-gamma binds di ...... gulation of exchange activity.
@nl
prefLabel
Phospholipase C-gamma binds di ...... gulation of exchange activity.
@en
Phospholipase C-gamma binds di ...... gulation of exchange activity.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
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P1433
P1476
Phospholipase C-gamma binds di ...... egulation of exchange activity
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932