Inhibition of fatty acid synthase by luteolin post-transcriptionally down-regulates c-Met expression independent of proteosomal/lysosomal degradation.
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Trans-ethnic meta-analysis identifies common and rare variants associated with hepatocyte growth factor levels in the Multi-Ethnic Study of Atherosclerosis (MESA).FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and GExpression of Fatty Acid Synthase Depends on NAC1 and Is Associated with Recurrent Ovarian Serous CarcinomasUp-regulated FASN expression promotes transcoelomic metastasis of ovarian cancer cell through epithelial-mesenchymal transitionMouse models of inherited cancer syndromesLuteolin exerts a marked antitumor effect in cMet-overexpressing patient-derived tumor xenograft models of gastric cancerEnhancing the anti-colon cancer activity of quercetin by self-assembled micelles.Reciprocal activating crosstalk between c-Met and caveolin 1 promotes invasive phenotype in hepatocellular carcinoma.The polyphenols (-)-epigallocatechin-3-gallate and luteolin synergistically inhibit TGF-β-induced myofibroblast phenotypes through RhoA and ERK inhibitionInhibition of the mevalonate pathway affects epigenetic regulation in cancer cells.Direct Inhibition of Cellular Fatty Acid Synthase Impairs Replication of Respiratory Syncytial Virus and Other Respiratory Viruses.Fatty acid synthase expression associated with NAC1 is a potential therapeutic target in ovarian clear cell carcinomas.Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice.Role of abnormal lipid metabolism in development, progression, diagnosis and therapy of pancreatic cancer.Molecular targets of luteolin in cancerEffect of brefelamide on HGF-induced survival of 1321N1 human astrocytoma cells.Metabolic and molecular regulation of dietary polyunsaturated fatty acids on prostate cancer.Quercetin inhibits HGF/c-Met signaling and HGF-stimulated melanoma cell migration and invasion.Anticancer effect and mechanism of polymer micelle-encapsulated quercetin on ovarian cancer.Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer.Immunohistochemical expressions of fatty acid synthase and phosphorylated c-Met in thyroid carcinomas of follicular origin.Upregulation of prostate-derived Ets factor by luteolin causes inhibition of cell proliferation and cell invasion in prostate carcinoma cells.HGF-induced invasion by prostate tumor cells requires anterograde lysosome trafficking and activity of Na+-H+ exchangers.Palmitoylation regulates the intracellular trafficking and stability of c-Met.Tumor suppressive microRNA-424 inhibits osteosarcoma cell migration and invasion via targeting fatty acid synthase.Fatty acid synthase expression in osteosarcoma and its correlation with pulmonary metastasis.microRNA-195 suppresses osteosarcoma cell invasion and migration in vitro by targeting FASN.Lysosome trafficking is necessary for EGF-driven invasion and is regulated by p38 MAPK and Na+/H+ exchangers.Iciartin, a novel FASN inhibitor, exerts anti-melanoma activities through IGF-1R/STAT3 signaling.Aggregation of lipid rafts activates c-met and c-Src in non-small cell lung cancer cells.Mechanism of metastasis suppression by luteolin in breast cancer.
P2860
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P2860
Inhibition of fatty acid synthase by luteolin post-transcriptionally down-regulates c-Met expression independent of proteosomal/lysosomal degradation.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on January 2009
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Inhibition of fatty acid synth ...... eosomal/lysosomal degradation.
@en
Inhibition of fatty acid synth ...... eosomal/lysosomal degradation.
@nl
type
label
Inhibition of fatty acid synth ...... eosomal/lysosomal degradation.
@en
Inhibition of fatty acid synth ...... eosomal/lysosomal degradation.
@nl
prefLabel
Inhibition of fatty acid synth ...... eosomal/lysosomal degradation.
@en
Inhibition of fatty acid synth ...... eosomal/lysosomal degradation.
@nl
P2093
P2860
P1476
Inhibition of fatty acid synth ...... eosomal/lysosomal degradation.
@en
P2093
David T Coleman
James A Cardelli
Rebecca Bigelow
P2860
P304
P356
10.1158/1535-7163.MCT-08-0722
P577
2009-01-01T00:00:00Z